The following drugs produce a prolonged action due to enterohepatic recirculation:

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RN ATI Capstone Pharmacology 2 Quiz Questions

Question 1 of 5

The following drugs produce a prolonged action due to enterohepatic recirculation:

Correct Answer: A

Rationale: Diazepam undergoes enterohepatic recirculation, contributing to its prolonged duration of action.

Question 2 of 5

A 56-year-old man with progressive, chronic renal impairment is awaiting renal replacement therapy. His treatment includes calcium carbonate tablets, furosemide, irbesartan and amlodipine. He is admitted severely unwell with a BP of 40 by palpation, pulse 112. An ECG shows a broad complex tachycardia with no P waves. Serum Ca2+ is 2.3 mmol/L, PO4 1.7 mmol/L, creatinine 785 μmol/L, Na+ 142 mmol/L, K+ 7.4 mmol/L. Which of the following would be appropriate management?

Correct Answer: C

Rationale: Severe hyperkalemia (K+ 7.4 mmol/L) in renal failure causes broad complex tachycardia, risking arrest. Amiodarone treats arrhythmias but not hyperkalemia's cause. Digoxin is contraindicated in hyperkalemia and renal failure. IV calcium gluconate stabilizes cardiac membranes, countering potassium's depolarizing effect, appropriate immediate management. Pacing or colestyramine (potassium binder) are secondary. Calcium's rapid action protects the heart, buying time for dialysis, critical in this life-threatening scenario.

Question 3 of 5

The patient has been depressed, and the physician plans to begin treatment with an antidepressant medication. In performing the initial assessment, what is the most important question for the nurse to ask?

Correct Answer: D

Rationale: Before antidepressants, assessing suicidal ideation is vital due to depression's suicide risk and SSRIs' potential to increase it initially. This ensures safety and guides monitoring. Alcohol use , allergies , and duration matter but are secondary to immediate risk. D prioritizes life-saving assessment, making it the most important question.

Question 4 of 5

During a blood transfusion, the patient begins to have chills and back pain. What is the nurse™s priority action?

Correct Answer: D

Rationale: The patient is exhibiting signs of a transfusion reaction, specifically indicating the possibility of a febrile non-hemolytic transfusion reaction. Chills and back pain are common symptoms of this type of reaction. The nurse's priority action in this situation is to discontinue the blood transfusion immediately to prevent further complications and potential harm to the patient. It is crucial to notify the prescriber promptly so that appropriate interventions can be initiated. Observing for other symptoms and slowing the infusion rate are important actions but may not be the priority in this scenario where the patient is experiencing signs of a possible transfusion reaction. It is not appropriate to tell the patient that these symptoms are a normal reaction, as they indicate a potential complication that needs immediate attention.

Question 5 of 5

A patient is taking azithromycin. Which nursing intervention(s) would the nurse plan to implement for this patient? (Select all that apply.)

Correct Answer: A

Rationale: Azithromycin is a macrolide antibiotic that can cause hepatotoxicity, so periodic liver function tests are necessary. Intravenous azithromycin should be diluted as per protocol, typically in 250-500 mL of fluid, not 50 mL. Loose stools or diarrhea may indicate Clostridium difficile-associated diarrhea, a serious adverse effect. Superinfections, such as oral thrush or vaginal yeast infections, should be reported promptly. Teaching the patient to take the oral drug 1 hour before or 2 hours after meals ensures optimal absorption. Avoiding antacids around the time of administration prevents interference with absorption.

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