ATI RN
Chapter 26 principles of pharmacology Questions
Question 1 of 5
The following drugs must be avoided in severe renal failure (glomerular filtration rate (GFR) <10 mL/min):
Correct Answer: D
Rationale: Metformin (D) must be avoided in severe renal failure (GFR <10 mL/min), risking lactic acidosis due to reduced clearance. Prednisolone (A) and amoxicillin (B) are safe with adjustment. Bumetanide (C) is usable. Oxytetracycline (original E) needs caution but not avoidance. Metformin's renal excretion, critical in diabetes, demands strict contraindication, a key safety concern in renal impairment pharmacology.
Question 2 of 5
The following characteristic of a drug tends to reduce its volume of distribution
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
Which of the following statements is False?
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
Drug (s) with saturation kinetics and narrow therapeutic index
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 5 of 5
Can be calculated for drugs administered intravenously (IV) by dividing the bolus dose administered by the initial resultant plasma concentration
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.