ATI RN
ATI Capstone Pharmacology Assessment 2 Questions
Question 1 of 9
The following drugs are reversible competitive antagonists:
Correct Answer: D
Rationale: Naloxone is a reversible competitive antagonist at opioid receptors, reversing opioid effects by competing for binding without activating the receptor.
Question 2 of 9
A patient undergoing chemotherapy for breast cancer asks why she is not receiving trastuzumab like her sister. Which response by the nurse is correct?
Correct Answer: D
Rationale: Trastuzumab is a targeted therapy used specifically for HER2-positive breast cancer. If the patient's cancer cells do not overexpress the HER2 receptor, trastuzumab will not be effective. The decision to use targeted therapy is based on the molecular characteristics of the tumor, not the patient's age, insurance coverage, or estrogen receptor status. The nurse should explain that targeted therapies are tailored to the specific biology of the cancer, and trastuzumab is only appropriate for HER2-positive tumors.
Question 3 of 9
The following drugs are considered safe in lactation:
Correct Answer: D
Rationale: These drugs are generally safe during breastfeeding, with minimal risk of transfer to the infant.
Question 4 of 9
The basic metric unit for the measurement of volume :
Correct Answer: C
Rationale: The basic metric unit for the measurement of volume is the liter. Although all the other options are also units used for measuring volume, the liter is considered the basic metric unit. It is often used for measuring larger volumes of liquids or gases. The other options are subunits of a liter:
Question 5 of 9
The following drugs are reversible competitive antagonists:
Correct Answer: D
Rationale: Naloxone is a reversible competitive antagonist at opioid receptors, reversing opioid effects by competing for binding without activating the receptor.
Question 6 of 9
Which assessment finding, by the nurse, is a priority concern when a client receives pseudoephedrine (Sudafed)?
Correct Answer: C
Rationale: Pseudoephedrine, an oral decongestant, stimulates alpha-adrenergic receptors, potentially causing cardiovascular effects like dysrhythmias due to its sympathomimetic action. An irregular heart rate of 82 is a priority concern, signaling possible arrhythmia, which could escalate to serious cardiac events, requiring immediate reporting. A mild fever or elevated respiratory rate could relate to the underlying condition (e.g., infection) rather than the drug. Dry mouth is a common, benign side effect. The nurse focuses on the irregular pulse as it aligns with pseudoephedrine's known risk of dysrhythmias, especially in susceptible patients, making choice C the most urgent finding to address.
Question 7 of 9
Which food items should the nurse advise a patient taking a monoamine oxidase inhibitor (MAOI) to avoid?
Correct Answer: C
Rationale: MAOIs (e.g., phenelzine) with tyramine-rich foods (chocolate, wine, fava beans) risk hypertensive crisis-per pharmacology-unlike juice/cheese or water/fish. Tyramine avoidance is critical, per diet.
Question 8 of 9
A patient with a new prescription for a HMG-CoA (statin) drug is instructed to take the
Correct Answer: D
Rationale: The nurse's best response is D: "This timeframe correlates better with the natural diurnal rhythm of cholesterol production." This explanation is accurate and helps the patient understand the rationale behind the timing of taking the HMG-CoA (statin) drug. Cholesterol production in the body typically follows a natural diurnal rhythm, with cholesterol synthesis peaking during the night. By taking the statin medication in the evening, it aligns with the body's cholesterol production pattern, making it more effective in reducing cholesterol levels. This explanation supports the patient's understanding of the importance of timing in maximizing the medication's effectiveness.
Question 9 of 9
A client is prescribed fluoxetine (Prozac) for depression. Which statement by the client indicates a need for further teaching?
Correct Answer: B
Rationale: Fluoxetine, an SSRI, treats depression but interacts with alcohol, worsening sedation or mood , indicating a teaching gap'clients must avoid it. Feeling better in weeks aligns with SSRI onset. Reporting suicidal thoughts is critical due to early risk. Morning dosing prevents insomnia. Drinking wine risks treatment failure or safety issues, critical in depression where stability is fragile. Further teaching must clarify this interaction, ensuring fluoxetine's efficacy and client well-being, making B the statement needing correction.