The following drugs are effectively administered by the rectal route to produce their systemic effect:

Questions 31

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ATI Proctored Exam Pharmacology Questions

Question 1 of 5

The following drugs are effectively administered by the rectal route to produce their systemic effect:

Correct Answer: A

Rationale: Indometacin, when administered rectally, bypasses first-pass metabolism, allowing rapid systemic absorption and therapeutic effect.

Question 2 of 5

Meperidine hydrochloride (Demerol) is given to a client who is experiencing post-operative pain. Which of the following are the side effects of the medication, except?

Correct Answer: B

Rationale: Meperidine hydrochloride (Demerol) is an opioid analgesic commonly used for post-operative pain management. The common side effects of meperidine include tremors, sweating, and dizziness. Diarrhea is not a common side effect associated with meperidine use. Opioid analgesics like meperidine more commonly cause constipation rather than diarrhea. Therefore, choice B is the correct answer as the side effect of diarrhea is not typically seen with meperidine administration.

Question 3 of 5

When monitoring a patient who has diabetes and is receiving a carbonic anhydrase inhibitor for edema, the nurse will monitor for which possible adverse effect?

Correct Answer: B

Rationale: Carbonic anhydrase inhibitors such as acetazolamide are commonly used to treat edema by promoting diuresis. However, one notable adverse effect of carbonic anhydrase inhibitors in patients with diabetes is the potential to elevate blood glucose levels. These medications can lead to an increase in blood glucose due to their effect on renal glucose reabsorption, resulting in hyperglycemia. Therefore, when monitoring a patient with diabetes who is receiving a carbonic anhydrase inhibitor for edema, it is crucial for the nurse to closely monitor the patient's blood glucose levels to prevent any adverse effects related to hyperglycemia.

Question 4 of 5

The client has MRSA and receives vancomycin (Vancocin) intravenously (IV). The nurse assesses an upper body rash and decreased urine output. What is the nurse's priority action?

Correct Answer: A

Rationale: Vancomycin is an antibiotic used to treat serious infections like MRSA, but it can cause significant adverse effects, including nephrotoxicity (kidney damage) and hypersensitivity reactions, such as rashes. The symptoms of an upper body rash and decreased urine output suggest a possible allergic reaction or renal impairment, both of which are potentially life-threatening if the drug continues to be administered. Holding the next dose prevents further exposure to the drug, which could exacerbate the reaction or damage, while notifying the physician ensures prompt medical evaluation and intervention. Obtaining an X-ray or urine specimen might provide additional data but doesn't address the immediate risk. Administering an antihistamine could mask symptoms without addressing the underlying issue, potentially delaying critical treatment. Thus, the priority is to stop the drug and seek physician guidance, making choice A the most appropriate action.

Question 5 of 5

The nursing instructor teaches student nurses about male reproductive function and the role of follicle-stimulating hormone (FSH). The instructor evaluates learning has occurred when the students make which statement?

Correct Answer: A

Rationale: Follicle-stimulating hormone (FSH) from the pituitary targets Sertoli cells in the testes to drive spermatogenesis, regulating sperm production and supporting male fertility. Androgen production, mainly testosterone, falls under luteinizing hormone (LH), not FSH, though both hormones interplay in reproduction. Testosterone synthesis in Leydig cells is LH-driven, not FSH, which focuses on sperm maturation. Progesterone, minimal in males, isn't FSH-regulated, being more female-centric. FSH's role in spermatogenesis is specific, distinguishing it from hormonal regulation and highlighting its importance in reproductive physiology, ensuring students understand its targeted action over broader endocrine effects.

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