The following drug is NOT correctly matched to its side effects

Correct Answer: B

Rationale: In this question, the correct answer is B) Paracetamol/bleeding. Paracetamol is not typically associated with causing bleeding as a side effect. A) Indomethacin is known to cause severe headaches due to cerebral vasoconstriction, making this option incorrect. C) Celecoxib is a COX-2 inhibitor and not structurally related to sulfonamides, so it does not typically cause a rash due to sulfonamide allergy. D) Ibuprofen is associated with Reye's syndrome in children with viral infections, particularly influenza or chickenpox, but this is a rare side effect and not a common one. Educationally, this question highlights the importance of understanding the side effects of common medications to ensure safe and effective pharmacological management. It emphasizes the need for healthcare professionals to be aware of potential adverse reactions to different drugs and the importance of accurate medication administration to prevent harm to patients.

Correct Answer: C

Rationale: The Food and Drug Administration (FDA) is the correct answer because it's the primary U.S. agency responsible for regulating drug development, including clinical trials, approval processes, and post-market surveillance to ensure drugs are safe and effective. The Drug Enforcement Agency (DEA) focuses on enforcing laws related to controlled substances, not drug development. The World Health Organization (WHO) is an international body that provides health guidelines but has no regulatory authority over U.S. drug development. The Bureau of Dangerous Drugs is an outdated or misnamed entity, not currently active in this role. The FDA's mandate under federal law makes it the sole agency fitting this description.

Correct Answer: B

Rationale: The National Formulary (NF) is correct because it, alongside the USP, sets official standards for drug formulations, approved by experts for consistency. The USP (United States Pharmacopeia) focuses on drug quality standards, not the formulary itself. The FDA regulates approval and safety, not formularies directly. The DEA manages controlled substances, not formularies. The NF's role in standardizing medication preparation distinguishes it here, as noted in pharmacology standards.

Correct Answer: D

Rationale: Purity' is correct because it sets the standard for a drug's composition, including type and concentration of substances, ensuring no contaminants. 'Potency' is strength, not the standard itself. 'Quality' is broader consistency, not specific to type/concentration. 'Efficacy' is effect, not composition standard. Purity, linked to USP/NF standards, ensures the drug matches its specified makeup, a critical regulatory aspect.

Correct Answer: B

Rationale: False' is correct because drug standards vary by state (e.g., prescribing laws) and country (e.g., FDA vs. EMA rules), despite some overlap like USP. 'True' is incorrect—uniformity isn't absolute; local regulations adapt standards. 'Not applicable' pads C/D for format. Variability in legal and quality controls, like scheduling or OTC rules, disproves universal standards.