ATI RN
Basic pharmacology principles Questions
Question 1 of 5
The following can reduce GFR:
Correct Answer: C
Rationale: Iodine-containing contrast media (C) reduce GFR, causing nephrotoxicity (e.g., contrast-induced nephropathy). Naproxen (A) and lisinopril (D) can too, correct but C is chosen. Ranitidine (B) has minimal effect. Amphotericin B (original E) is nephrotoxic. GFR reduction, critical in renal pharmacokinetics, alters drug clearance, necessitating monitoring in imaging or therapy, a key risk factor.
Question 2 of 5
The following drugs do not readily cross to the CNS in meningitis
Correct Answer: E
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
Extraction ratio (E) of a drug is
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
Which of the following definition (s) is (are) incorrect
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 5 of 5
Used to describe drugs with identical areas under the curve (AUCs)
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.