ATI RN
Central Nervous System Stimulants and Related Drugs NCLEX Style Questions Questions
Question 1 of 5
The following adverse effect of corticosteroids is due to their mineralocorticoid action
Correct Answer: B
Rationale: Corticosteroids can cause sodium retention, leading to hypertension due to their mineralocorticoid effects.
Question 2 of 5
Peak serum level of orally administered lithium is usually achieved in
Correct Answer: C
Rationale: Lithium reaches its peak serum levels typically within 2 to 4 hours after oral administration.
Question 3 of 5
Which of the following drugs was most likely prescribed for the 12-year-old girl with refractory absence seizures?
Correct Answer: B
Rationale: In this case, the neurologist decided to add a second-generation antiepileptic drug that blocks voltage-gated Na+ and Ca2+ channels and may inhibit the synaptic release of glutamate. Among the choices, Lamotrigine fits this description as it is known to block voltage-gated sodium channels, making it the most likely drug prescribed for the patient.
Question 4 of 5
A patient with multiple sclerosis is having muscle spasticity. The nurse anticipates which drug will be prescribed to treat the patient’s spasticity?
Correct Answer: C
Rationale: The correct answer is C: Cyclobenzaprine. Cyclobenzaprine is a centrally acting muscle relaxant commonly used to treat muscle spasticity in conditions like multiple sclerosis. It works by inhibiting nerve impulses to reduce muscle spasms. Neostigmine (A) is a cholinesterase inhibitor used for myasthenia gravis, not spasticity. Ropinirole (B) is a dopamine agonist used for Parkinson's disease and restless legs syndrome, not spasticity. Pyridostigmine (D) is also a cholinesterase inhibitor used for myasthenia gravis, not spasticity.
Question 5 of 5
Which of the following are NOT correctly paired?
Correct Answer: D
Rationale: Buspirone (choice A), Alprazolam (choice B), and Baclofen (choice C) are correctly paired (anxiolytic, some antidepressant effect, less sedative muscle relaxant). Oxazepam (choice D), a benzodiazepine, isn't a TCA, making it the incorrect pair. This tests drug classification.