ATI RN
Chapter 14 Drugs for the Reproductive System Questions
Question 1 of 5
The estrogen commonly used for hormone replacement therapy in menopausal women is:
Correct Answer: D
Rationale: The correct answer is D: Conjugated estrogens. Conjugated estrogens are derived from the urine of pregnant mares and contain a mixture of estrogens like estrone and equilin. They are commonly used for hormone replacement therapy in menopausal women due to their effectiveness in relieving menopausal symptoms. A: Ethinylestradiol is a synthetic estrogen commonly used in birth control pills, not as hormone replacement therapy in menopausal women. B: Estradiol benzoate is a form of estradiol used in veterinary medicine, not typically used in hormone replacement therapy for menopausal women. C: Diethylstilbestrol is a synthetic nonsteroidal estrogen that has been largely discontinued due to its association with serious health risks, not commonly used for hormone replacement therapy in menopausal women.
Question 2 of 5
The most suitable vitamin D preparation for vitamin D dependent rickets is:
Correct Answer: D
Rationale: The correct answer is D: Calcitriol. Calcitriol is the active form of vitamin D and is the most suitable preparation for vitamin D dependent rickets as it directly increases calcium absorption in the intestines and promotes bone mineralization. Calcitriol is essential for regulating calcium and phosphorus levels in the body. Choice A, Calciferol, is a general term for vitamin D compounds and is not specific enough for rickets treatment. Choice B, Cholecalciferol, is the precursor form of vitamin D and needs to be converted to calcitriol in the body. Choice C, Calcifediol, is an intermediate form that also requires conversion to calcitriol for biological activity. Therefore, calcitriol is the most appropriate choice for treating vitamin D dependent rickets due to its direct action on calcium metabolism and bone health.
Question 3 of 5
Bone resorption is accelerated by:
Correct Answer: B
Rationale: The correct answer is B: Parathormone. Parathormone stimulates osteoclast activity, which leads to increased bone resorption. Estrogens (choice A) actually inhibit bone resorption. Bisphosphonates (choice C) are used to decrease bone resorption. Calcitonin (choice D) also inhibits bone resorption by blocking osteoclast activity. Therefore, the correct choice is parathormone as it directly accelerates bone resorption by stimulating osteoclasts.
Question 4 of 5
Actions of oxytocin include the following except:
Correct Answer: A
Rationale: 1. Oxytocin is a hormone that primarily functions in inducing uterine contractions and milk let-down. 2. Vasoconstriction is not a known physiological action of oxytocin. 3. Increased water reabsorption, mammary contraction, and prostaglandin release are all effects of oxytocin. 4. Therefore, the correct answer is A: Vasoconstriction, as it is not a typical action of oxytocin.
Question 5 of 5
Concurrent use of the following drug is likely to cause failure of oral contraception:
Correct Answer: B
Rationale: The correct answer is B: Rifampicin. Rifampicin is an enzyme inducer that can accelerate the metabolism of oral contraceptives, leading to decreased effectiveness and potential contraceptive failure. It induces hepatic enzymes, increasing the metabolism of estrogen and progestin in oral contraceptives, reducing their efficacy. Isoniazid (A), Cimetidine (C), and Propranolol (D) do not have significant interactions with oral contraceptives.