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Drugs Affecting the Female Reproductive System NCLEX Quizlet Questions
Question 1 of 5
The duration of action of insulin-zinc suspension (lente insulin) is:
Correct Answer: B
Rationale: The correct answer is B: 8-10 hours. Lente insulin is a type of intermediate-acting insulin that typically lasts around 8-10 hours. This is because it is a mixture of insulin crystals and zinc, which delays its absorption and extends its duration of action. Choice A (2-4 hours) is too short for lente insulin. Choice C (20-24 hours) and D (30-36 hours) are too long for lente insulin, which is considered intermediate-acting. Therefore, the correct answer is B as it aligns with the expected duration of action for lente insulin.
Question 2 of 5
The second generation sulfonylurea hypoglycaemics differ from the first generation ones in that they:
Correct Answer: D
Rationale: Step 1: Second generation sulfonylureas like glimepiride and glipizide are less likely to cause hypoglycemic reactions compared to first generation ones like chlorpropamide and tolbutamide. Step 2: This is because second generation drugs have a shorter duration of action and are more selective for pancreatic beta cells, reducing the risk of hypoglycemia. Step 3: Therefore, option D is correct as it accurately reflects the difference between the two generations in terms of hypoglycemic risk. Summary: - Option A is incorrect because both generations can be potent in lowering blood sugar. - Option B is incorrect as second generation drugs are not necessarily longer acting. - Option C is incorrect as sulfonylureas lower blood sugar regardless of the patient's diabetic status.
Question 3 of 5
The hypoglycaemic action of sulfonylureas is likely to be reduced by the concurrent use of:
Correct Answer: B
Rationale: The correct answer is B, Propranolol. Propranolol is a beta-blocker that can mask the symptoms of hypoglycemia, making it difficult to recognize and treat low blood sugar levels. This can lead to severe hypoglycemia if not properly managed. Hydrochlorothiazide (A) is a diuretic, Theophylline (C) is a bronchodilator, and Aspirin (D) is a pain reliever, none of which directly affect the hypoglycemic action of sulfonylureas.
Question 4 of 5
Choose the correct statement(s) about pioglitazone:
Correct Answer: D
Rationale: Step 1: Pioglitazone is a thiazolidinedione that acts as an agonist on nuclear peroxisome proliferator receptor γ (PPAR-γ). Step 2: Activation of PPAR-γ enhances transcription of insulin responsive genes. Step 3: By enhancing insulin sensitivity and glucose uptake in peripheral tissues, pioglitazone lowers blood sugar in type 2 diabetes mellitus without causing hyperinsulinemia. Step 4: Therefore, all the statements A, B, and C are correct, making option D the correct answer. Other choices are incorrect as they do not accurately describe the mechanism of action and effects of pioglitazone.
Question 5 of 5
Glucagon release from pancreas is stimulated by:
Correct Answer: D
Rationale: The correct answer is D: Adrenaline. Glucagon release is stimulated by low blood glucose levels, which triggers the release of adrenaline. Adrenaline signals the liver to release stored glucose, raising blood sugar levels. High blood glucose levels (choice A) would not stimulate glucagon release. Insulin (choice B) decreases blood glucose levels and inhibits glucagon release. Somatostatin (choice C) also inhibits glucagon release.