The drug of choice for manic-depressive psychosis is:

Correct Answer: D

Rationale: The correct answer is D: Lithium carbonate. Lithium is the drug of choice for manic-depressive psychosis (now known as bipolar disorder) due to its mood-stabilizing properties. It helps to reduce the frequency and severity of manic episodes. Imipramine (A) is a tricyclic antidepressant, not typically used for bipolar disorder. Chlordiazepoxide (B) is a benzodiazepine used for anxiety and alcohol withdrawal, not for bipolar disorder. Isocarboxazid (C) is a monoamine oxidase inhibitor used for depression, not specifically for bipolar disorder. In summary, lithium is the preferred treatment for bipolar disorder due to its proven efficacy in managing manic episodes.

Correct Answer: D

Rationale: The correct answer is D: All of the above. Benzodiazepines, when used in combination with ethanol, morphine, or chlorpromazine, can lead to additive CNS depression due to their similar mechanisms of action. Ethanol enhances the sedative effects of benzodiazepines, morphine can increase the risk of respiratory depression when combined with benzodiazepines, and chlorpromazine can potentiate the sedative effects. Therefore, using benzodiazepines with any of these substances can result in increased CNS depression. The other choices (A, B, and C) are incorrect because each of these substances alone can potentiate CNS depression when combined with benzodiazepines, making choice D the most comprehensive and correct option.

Correct Answer: A

Rationale: The correct answer is A: Enflurane. Enflurane can lower the seizure threshold, making it risky for patients with a history of seizure disorders. Nitrous oxide (B), Sevoflurane (C), and Desflurane (D) are considered safer options and do not have as significant an effect on seizure threshold. Therefore, Enflurane should be avoided in patients with a history of seizure disorders to prevent potential complications.

Correct Answer: A

Rationale: Step-by-step rationale: - Misoprostol is a synthetic prostaglandin E1 analog used to prevent gastric ulcers, not an antacid. - Maalox, Mylanta, and Almagel are all antacids used to neutralize stomach acid. - Misoprostol increases gastric mucus production, inhibits acid secretion, and promotes healing of the stomach lining. - Therefore, the correct answer is A (Misoprostol) as it is not an antacid but rather a medication used to prevent ulcers.

Correct Answer: B

Rationale: The correct answer is B: Streptokinase. Streptokinase is a fibrinolytic drug that helps break down blood clots by activating plasminogen. This process helps improve blood flow in conditions like myocardial infarction or stroke. Ticlopidine (A) is an antiplatelet drug, Aspirin (C) is also an antiplatelet agent, and Warfarin (D) is an anticoagulant. These drugs work differently from fibrinolytics and do not directly dissolve blood clots like Streptokinase does.