ATI RN
ABVD chemotherapy drugs Questions
Question 1 of 5
The drug commonly associated with acute hemolytic reaction in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency is:
Correct Answer: A
Rationale: Sulfonamides can cause hemolysis in G6PD-deficient patients due to oxidative stress.
Question 2 of 5
The following antibiotic binds to sites on the 30S subunit of bacterial ribosome leading to production of defective bacterial proteins:
Correct Answer: A
Rationale: Streptomycin binds to the 30S ribosomal subunit, causing misreading of mRNA.
Question 3 of 5
Ticarcillin is relatively unique among all the penicillins because it poses a greater risk of a relatively unique side effect or adverse response. Which of the following best summarizes what that unique unwanted effect is?
Correct Answer: D
Rationale: Ticarcillin’s high sodium content can cause hypertension, hypervolemia, and bleeding tendencies.
Question 4 of 5
A patient develops antibiotic-associated pseudomembranous colitis (AAPMC) in response to drug therapy. Which of the following was the most likely cause of this severe problem?
Correct Answer: C
Rationale: Clindamycin is a common cause of C. difficile-associated pseudomembranous colitis (repeated question).
Question 5 of 5
A 50-year-old man with Type 2 diabetes develops an otitis from which Pseudomonas organisms are cultured. Topical therapy with polymyxin B is effective. Which of the following best explains the drug's mechanism of action?
Correct Answer: A
Rationale: Polymyxin B disrupts bacterial membrane permeability, targeting gram-negative bacteria like Pseudomonas.