The diagnostic triad of opioid overdosage is:

Correct Answer: B

Rationale: The correct answer is B: Coma, depressed respiration, and miosis. In opioid overdosage, coma occurs due to central nervous system depression, depressed respiration is a result of respiratory center suppression, and miosis is a classic sign of opioid toxicity due to the activation of the parasympathetic nervous system. Mydriasis (pupil dilation) is not a common feature in opioid overdosage. Chills and abdominal cramps are more indicative of opioid withdrawal rather than overdose. Tremor and vomiting are not typically part of the diagnostic triad of opioid overdosage.

Correct Answer: B

Rationale: The correct answer is B (2-3 weeks) because antidepressants typically require time to build up in the body and affect neurotransmitter levels. It takes time for the brain to adapt to the medication and for changes in mood to become noticeable. A: 2-3 days is too short for significant effects. C: 24 hours is not enough time for the medication to take full effect. D: 2-3 months is too long for most individuals to wait for improvement.

Correct Answer: D

Rationale: The correct answer is D: It has a high potential of toxicity. Piracetam is known for its low toxicity and safety profile, making it a popular nootropic. A: It is not a GABA derivative, but it does modulate some GABA receptors. B: It does influence neuro-vegetative functions positively. C: Improvement with piracetam typically starts earlier, around the 2nd week, rather than the 3rd week as mentioned in the incorrect choice.

Correct Answer: D

Rationale: The correct answer is D because cocaine intoxication presents with a variety of symptoms including clouding of consciousness, lightness of body, feeling of flight, wave warmth, physical bliss, motionlessness, clear consciousness, improved mood, influx of physical and spiritual forces, locomotive and speech excitation, and reappraisal of personality. These symptoms collectively represent the typical effects of cocaine intoxication. Choices A, B, and C each only describe a subset of the symptoms and experiences associated with cocaine intoxication, whereas choice D encompasses all the possible manifestations. Therefore, the correct answer is D as it includes all the symptoms that can be observed during cocaine intoxication.

Correct Answer: C

Rationale: The correct answer is C: Desoxiribonuclease. Desoxiribonuclease is an enzyme that breaks down DNA, not disulfide bonds of proteoglycans. A: Acetylcysteine breaks disulfide bonds, reducing sputum viscosity. B: Ambroxol disrupts disulfide bonds, aiding in sputum clearance. D: Bromhexin also works by disrupting disulfide bonds, facilitating mucus clearance.