ATI RN
Pediatric Immune Disorder Test Questions Questions
Question 1 of 5
The currently available vaccine to prevent hepatitis A infection is...?
Correct Answer: C
Rationale: The hepatitis A vaccine is an inactivated (killed) virus vaccine, providing immunity without risk of infection.
Question 2 of 5
The most likely diagnosis in the patient described in Question 2 is
Correct Answer: C
Rationale: Chronic granulomatous disease (CGD) is indicated by recurrent infections with catalase-positive organisms like Staphylococcus aureus, including lymphadenitis and liver abscesses, due to defective phagocyte function. Bruton agammaglobulinemia involves B-cell defects, AIDS is a T-cell disorder, and Kostmann disease is severe congenital neutropenia, none of which fit this presentation as well as CGD.
Question 3 of 5
Matching: Immunodeficiency - Chromosome 22q12
Correct Answer: A
Rationale: DiGeorge syndrome is caused by a 22q11.2 deletion (often written as 22q12 in shorthand), affecting thymic development. No other listed condition matches this chromosomal defect.
Question 4 of 5
The initial screening laboratory evaluation of a child with recurrent infections for possible immunodeficiency includes all of the following EXCEPT
Correct Answer: D
Rationale: The NBT test is a specific diagnostic test for CGD, not part of initial screening. CBC, lymphocyte count, and immunoglobulin levels are broad screening tools for immunodeficiency.
Question 5 of 5
What is the phagocytic defect of chronic granulomatous disease?
Correct Answer: C
Rationale: CGD is caused by an inability to activate the neutrophil respiratory burst, impairing oxidative killing of ingested microbes.