The current criteria for the diagnosis of type 1 and type 2 DM is a fasting blood glucose that exceeds

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Pediatric Endocrine Exam Questions Questions

Question 1 of 5

The current criteria for the diagnosis of type 1 and type 2 DM is a fasting blood glucose that exceeds

Correct Answer: D

Rationale: Fasting glucose >125 mg/dL (D) is the ADA criterion for diabetes diagnosis.

Question 2 of 5

Microvascular complications of DM include

Correct Answer: A

Rationale: Nephropathy (A) is a microvascular complication; others (B-D) are macrovascular.

Question 3 of 5

Donohue syndrome is characterized by the following EXCEPT

Correct Answer: B

Rationale: Donohue syndrome (leprechaunism) features fasting hyperglycemia (not hypoglycemia, B) due to severe insulin resistance.

Question 4 of 5

All the following are widely used modalities for treatment of inborn errors of metabolism (IEM) EXCEPT

Correct Answer: B

Rationale: Special diets (A), dialysis (C), transplantation (D), and metabolite replacement (E) are established IEM treatments. Gene therapy (B) is experimental and not yet widely used.

Question 5 of 5

In the classic phenylketonurea, the affected infant is normal at birth, intellectual disability develops gradually if the infant remains untreated, and cognitive delay may not be evident for the first few months. All the following are true about neonatal screening program of this condition EXCEPT

Correct Answer: B

Rationale: The Guthrie test (A) was first, levels rise early (C), modern methods reduce false positives (D), and confirmation is needed (E). However, the optimal Guthrie test time is 24-48 hours, not 7-14 days, to ensure feeding elevates phenylalanine.

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