ATI RN
Pediatric Immunization Practice Questions Questions
Question 1 of 5
The complement system plays a key role in the host defense process. Which of the following components of this system is the most important in chemotaxis?
Correct Answer: D
Rationale: C5a is the most potent complement-derived chemoattractant for neutrophils.
Question 2 of 5
A 17-month-old girl presented with history of recurrent attacks of pneumonia since the age of 8 months. You suspect a predominant B-cell defect. Of the following, the BEST simple initial screening test is
Correct Answer: D
Rationale: Isohemagglutinins titer is a functional test for B-cell activity, measuring naturally occurring antibodies (anti-A/anti-B), making it an effective initial screen for B-cell defects.
Question 3 of 5
All the following are features of ataxia-telangiectasia EXCEPT
Correct Answer: A
Rationale: Ataxia-telangiectasia involves neurologic decline, malignancies, and sinopulmonary infections, but hepatic manifestations are not a typical feature.
Question 4 of 5
A 4-year-old boy presented with high fever, decreased appetite, aphthous stomatitis, and cellulitis of the right calf muscle. His absolute neutrophil count (ANC) was 600/μL. The MOST likely organisms causing this condition are
Correct Answer: D
Rationale: Neutropenia predisposes to bacterial infections; Staphylococcus aureus and gram-negative bacteria (e.g., Pseudomonas) are common culprits in cellulitis and stomatitis.
Question 5 of 5
In patient with Chédiak-Higashi syndrome, the only curative therapy is hematopoietic stem cell transplantation which correct all the following EXCEPT
Correct Answer: A
Rationale: HSCT corrects immune and hematologic defects in Chédiak-Higashi but not progressive neuropathy, which is neurologic in origin.