ATI RN
Cardiovascular Pharmacology Drug Class Questions
Question 1 of 5
The combination of naltrexone and disulfiram should be avoided since both drugs are potential hepatotoxins.
Correct Answer: A
Rationale: The correct answer is A: TRUE. Both naltrexone and disulfiram are known to potentially cause liver toxicity individually. When used together, the risk of hepatotoxicity is significantly increased due to their combined effects on the liver. Therefore, the combination of naltrexone and disulfiram should be avoided to prevent liver damage. Choice B: FALSE is incorrect because combining two hepatotoxins like naltrexone and disulfiram can indeed lead to liver toxicity. Choice C: None is incorrect as there is a clear recommendation to avoid the combination of these two drugs due to the risk of hepatotoxicity. Choice D: All is incorrect as not all combinations of drugs are hepatotoxins, but specifically the combination of naltrexone and disulfiram poses a risk of liver damage.
Question 2 of 5
Indicate the nootropic agent:
Correct Answer: D
Rationale: Step-by-step rationale: 1. Nootropic agents enhance cognitive function. 2. Piracetam is a well-known nootropic agent. 3. It improves memory, focus, and overall brain function. 4. Sydnocarb is a stimulant, not a nootropic. 5. Eleuterococci extract is an adaptogen, not a nootropic. 6. Fluoxetine is an antidepressant, not a nootropic. Summary: Piracetam is the correct answer as it aligns with the definition and effects of a nootropic agent. Sydnocarb, Eleuterococci extract, and Fluoxetine do not possess the specific cognitive-enhancing properties of a true nootropic agent.
Question 3 of 5
Which of the following anxiolytics has minimal abuse liability?
Correct Answer: B
Rationale: The correct answer is B: Buspirone. Buspirone is a non-benzodiazepine anxiolytic that has minimal abuse potential, as it does not act on the GABA receptor like benzodiazepines do. Buspirone's mechanism of action involves serotonin and dopamine receptors, making it less likely to be abused compared to benzodiazepines. Rationale: A: Oxazepam is a benzodiazepine, which can lead to dependence and abuse due to its effects on the GABA receptor. C: Flumazenil is a benzodiazepine receptor antagonist used to reverse the effects of benzodiazepine overdose, not an anxiolytic. D: Alprazolam is a benzodiazepine with high abuse potential due to its rapid onset of action and reinforcing effects.
Question 4 of 5
Indicate the inhaled anesthetic,which reduces arterial pressure and heart rate:
Correct Answer: A
Rationale: The correct answer is A: Isoflurane. Isoflurane is known to reduce arterial pressure and heart rate. It achieves this through its vasodilatory effects, leading to decreased systemic vascular resistance and cardiac depression. Halothane can cause arrhythmias and increased heart rate. Desflurane can increase heart rate and arterial pressure due to sympathetic activation. Nitrous oxide typically has minimal effects on heart rate and arterial pressure. Therefore, the correct choice is isoflurane due to its specific physiological effects that result in reduced arterial pressure and heart rate.
Question 5 of 5
Which of the following drugs may cause reversible gynecomastia?
Correct Answer: C
Rationale: Rationale: Cimetidine is an H2 receptor antagonist that can cause reversible gynecomastia by inhibiting androgen receptors. This leads to increased estrogen levels and breast tissue growth in males. Omeprazole (A), Pirenzepine (B), and Sucralfate (D) are not associated with gynecomastia as they do not affect hormone levels in the same way as cimetidine.