ATI RN
Toxicological drugs Questions
Question 1 of 5
The combination of coma, dilated pupils, hyperreflexia and tachycardia is consistent with overdose of the following drugs when taken alone:
Correct Answer: B
Rationale: Dosulepin (B) and amitriptyline (D), tricyclic antidepressants, cause coma, dilated pupils, hyperreflexia, and tachycardia in overdose. Co-dydramol (A) and lorazepam (E) cause sedation, and aspirin (C) causes metabolic disturbances.
Question 2 of 5
The following are confirmed aphrodisiacs:
Correct Answer: D
Rationale: None of these (A-E) are scientifically confirmed aphrodisiacs; they are anecdotal or lack robust evidence in clinical toxicology.
Question 3 of 5
Methadone:(Select one that does not apply)
Correct Answer: B
Rationale: Methadone causes dependence (A), is often given as an elixir (C), depresses the cough centre (D), and is reversed by naloxone (E). B is incorrect as prescribing regulations vary by country and don’t universally require special licences only for registered addicts.
Question 4 of 5
Features of the opioid withdrawal syndrome include:
Correct Answer: D
Rationale: Opioid withdrawal includes yawning (A), rhinorrhoea (B), mydriasis (C), diarrhoea (D), and tremor (E), all part of the autonomic and neurological response to cessation.
Question 5 of 5
There is an increased rate of metabolism of the following drugs in smokers:
Correct Answer: A
Rationale: Smoking induces CYP1A2, increasing metabolism of diazepam (A) and theophylline (E). Phenytoin (B), ethanol (C), and warfarin (D) are less consistently affected by smoking-induced metabolism.