ATI RN
Virtual ATI Pharmacology Assessment Questions
Question 1 of 9
The client receives beclomethasone (Beconase) intranasally as treatment for allergic rhinitis. He asks the nurse if this drug is safe because it is a glucocorticoid. What is the best response by the nurse?
Correct Answer: A
Rationale: Beclomethasone's low systemic absorption minimizes serious effects , reassuring its safety for rhinitis. Swallowing , duration , and dosing aren't primary concerns. A aligns with its safety profile, making it the best response.
Question 2 of 9
The nursing mother asks the nurse if it is all right to take St. John's wort for mild depression. What is the best response by the nurse?
Correct Answer: C
Rationale: St. John's wort, an herbal antidepressant, passes into breast milk, potentially affecting the baby-e.g., sedation or colic-making it unsafe without medical advice. Allergies lack evidence as a concern. Milk production isn't a known issue. Taste changes are unproven. Excretion risk is the primary concern, supported by pharmacokinetics, prioritizing infant safety.
Question 3 of 9
A month after receiving a blood transfusion an immunocompromised male patient develops a fever, liver abnormalities, a rash, and diarrhea. The nurse would suspect this patient has:
Correct Answer: B
Rationale: Graft-versus-host disease (GVHD) is a potential complication in immunocompromised patients after receiving blood transfusions. It occurs when donor lymphocytes attack the recipient's tissues, leading to symptoms such as fever, rash, liver dysfunction, and diarrhea. This condition typically arises weeks to months after transfusion. An allergic response to medication would not explain the systemic symptoms. Myelosuppression is unrelated to transfusion. Therefore, GVHD is the most likely diagnosis in this scenario.
Question 4 of 9
Which of the following drugs is contraindicated if there is a history of acute porphyria?
Correct Answer: C
Rationale: Acute porphyria involves heme synthesis defects, triggered by drugs inducing hepatic enzymes (e.g., CYP450). Quinine, used in malaria, isn't a major porphyria trigger. Atenolol, a beta-blocker, is porphyrin-safe, with minimal enzyme induction. Oral contraceptives, containing estrogens/progestins, induce ALA synthase, exacerbating acute porphyria, making them contraindicated. Heparin and amoxicillin don't significantly affect porphyrin metabolism. The contraceptive link reflects hormonal exacerbation of porphyric attacks, critical for safe prescribing in this rare condition.
Question 5 of 9
A patient who has been diagnosed with social anxiety disorder will begin taking venlafaxine(Effexor). The nurse who performs a medication and dietary history will be concerned about ingestion of which substance or drug?
Correct Answer: D
Rationale: St. John's wort is an herbal supplement that can interact with many medications, including venlafaxine (Effexor). When taken together, it can decrease the effectiveness of venlafaxine by increasing its metabolism, potentially leading to reduced therapeutic effects. This interaction can also increase the risk of side effects or adverse reactions. Therefore, the nurse should be concerned about the ingestion of St. John's wort when a patient is taking venlafaxine to ensure proper medication management and effectiveness. It is important for patients to inform healthcare providers about all supplements they are taking to prevent harmful interactions.
Question 6 of 9
A 45-year-old woman undergoes a complete hysterectomy for leiomyomas and dysfunctional uterine bleeding. The surgeon wants to prescribe a pain relief medication following the procedure, but the patient's serum creatinine is 1.2 mg/dL. Which of the following pain relief medications should the surgeon avoid prescribing?
Correct Answer: D
Rationale: Post-hysterectomy pain with creatinine 1.2 mg/dL (mild renal impairment) contraindicates Ketorolac , an NSAID. Its renal toxicity risks harm. Acetaminophen , Codeine , Hydrocodone , and Oxycodone (E) are safer. Ketorolac's prostaglandin inhibition could worsen kidney function.
Question 7 of 9
A male patient is to begin therapy with isotretinoin and asks, 'What do I have to remember to do while taking this medicine?' How would the nurse respond? (Select all that apply.)
Correct Answer: B
Rationale: Isotretinoin is a potent medication with significant side effects and precautions. Patients should avoid sunlight (A) due to increased photosensitivity. Regular laboratory tests (C) are necessary to monitor liver function and lipid levels. Two forms of contraceptives (D) are required for females due to the high risk of teratogenicity. Monitoring weight (B) is not typically associated with isotretinoin use.
Question 8 of 9
The client receives hydroxychloroquine sulfate (Plaquenil). Which test does the nurse tell the client should be done on a regular basis?
Correct Answer: B
Rationale: Hydroxychloroquine risks retinal damage-regular eye exams (e.g., yearly) detect it early, per safety. Potassium, glucose, and BP aren't directly tied-retinopathy is key. Exams monitor vision, per protocol.
Question 9 of 9
The client receives beclomethasone (Beconase) intranasally as treatment for allergic rhinitis. He asks the nurse if this drug is safe because it is a glucocorticoid. What is the best response by the nurse?
Correct Answer: A
Rationale: Beclomethasone's low systemic absorption minimizes serious effects , reassuring its safety for rhinitis. Swallowing , duration , and dosing aren't primary concerns. A aligns with its safety profile, making it the best response.