ATI RN
Intro to Pharmacology ATI Questions
Question 1 of 5
The client is receiving warfarin (Coumadin) for a deep vein thrombosis. Which food should the nurse instruct the client to avoid in large amounts?
Correct Answer: A
Rationale: Warfarin, an anticoagulant, inhibits vitamin K-dependent clotting factors. Spinach is high in vitamin K, which can counteract warfarin's effect, reducing its efficacy and increasing clot risk if consumed in large amounts. The nurse must instruct avoidance to maintain therapeutic INR levels. Potatoes and bananas have minimal vitamin K and don't significantly affect warfarin. Chicken is protein-rich, not vitamin K-rich, posing no issue. Consistent vitamin K intake is key, but large amounts of spinach could destabilize anticoagulation, risking thrombus progression. This aligns with warfarin's pharmacodynamics, where dietary education prevents therapeutic failure. Potatoes, bananas, and chicken lack this interaction, making spinach the priority to limit. Thus, A is the correct choice, ensuring the client understands how to support treatment efficacy and safety through diet management.
Question 2 of 5
A 36-year-old man is brought to the emergency department after being involved in a one-car motor vehicle accident where his car struck a telephone pole. He is a known chronic alcoholic. He smells alcohol on his breath, and his blood alcohol level is 300 mg/dL. Which of the following treatments should be given to him if he goes into alcohol withdrawal?
Correct Answer: B
Rationale: Alcohol withdrawal in a chronic alcoholic (300 mg/dL) requires lorazepam . This benzodiazepine mimics alcohol's GABA enhancement, preventing seizures and agitation. Buspirone treats anxiety, not withdrawal. Pentobarbital is excessive. Phenytoin targets seizures alone. Saline (E) supports but doesn't treat. Lorazepam's safety is key.
Question 3 of 5
The nurse is conducting medication education about the difference between potency and efficacy to a group of patients. The nurse correctly determines that learning has occurred when the patients make which response?
Correct Answer: B
Rationale: Efficacy (max effect) trumps potency (dose needed) for ‘best'-a high-efficacy drug fully relieves symptoms, unlike high-potency alone. Potency doesn't guarantee outcome. Efficacy doesn't mean fewer side effects-safety varies. Low-potency drugs can be effective but aren't side-effect-free. Greatest efficacy reflects learning, prioritizing treatment success.
Question 4 of 5
A 52-year-old man with asthma treated with a β2 agonist via inhaler has been having difficulty with therapy because of persistent changes in blood pressure, nausea, vomiting, and hypomagnesemia. Which of the following medications would be best for this patient?
Correct Answer: D
Rationale: β2-agonist side effects (BP changes, nausea, hypomagnesemia) suggest overuse. Ipratropium , an anticholinergic bronchodilator, avoids these. Options , , persist with β2-agonists, risking side effects. Epinephrine (E) worsens them. Ipratropium's different mechanism improves asthma control safely.
Question 5 of 5
Which combination of local anesthesia produces EMLA ( Eutectic Mixture of Local Anesthetics):
Correct Answer: B
Rationale: EMLA (Eutectic Mixture of Local Anesthetics) is a commonly used topical local anesthetic cream. It contains a combination of lidocaine and prilocaine. This combination of local anesthetics work together to provide effective pain relief when applied to the skin before certain medical procedures like needle insertion, laser treatment, or minor skin surgeries. Lidocaine and prilocaine work by blocking nerve signals in the skin, reducing sensations of pain and discomfort in the area where the cream is applied.