ATI RN
ATI Pharmacology Assessment 2 Questions
Question 1 of 5
The classi昀椀cation of digoxin is:
Correct Answer: D
Rationale: Digoxin belongs to the class of drugs known as cardiac glycosides. Cardiac glycosides are a group of compounds derived from plants and some animals that have the ability to increase the contractility of the heart muscle. Digoxin is commonly used to treat conditions such as congestive heart failure and irregular heart rhythms. It works by inhibiting the sodium-potassium pump in heart muscle cells, leading to an increase in intracellular calcium levels and subsequently improving the heart's pumping ability.
Question 2 of 5
A nurse is giving a patient a loading dose of 1 mg of an antiarrhythmic drug to treat atrial flutters. Which of the following is most likely the drug being administered?
Correct Answer: A
Rationale: Digoxin is commonly used to treat atrial flutter and atrial fibrillation by helping to control the heart rate. A loading dose may be given initially to reach therapeutic levels quickly. This medication acts by increasing the force of the heart's contractions and slowing down the heart rate. Propranolol (Choice B) is a beta-blocker used to treat various heart conditions, but it is not typically used for atrial arrhythmias like atrial flutter. Ibuprofen (Choice C) is a nonsteroidal anti-inflammatory drug used for pain and inflammation, not for cardiac arrhythmias. Lithium (Choice D) is a mood-stabilizing medication often used for bipolar disorder and is not indicated for atrial flutter treatment.
Question 3 of 5
Local vasoconstriction is of short duration and can be prolonged by application of:
Correct Answer: C
Rationale: Thromboxane is a vasoconstrictor that is released by platelets during the process of blood clotting. Local vasoconstriction is a temporary response that occurs to reduce bleeding at the site of injury. Thromboxane plays a role in this process by constricting the blood vessels temporarily to limit blood flow to the injured area. By prolonging the application of thromboxane, vasoconstriction can be prolonged to support the clotting process and minimize bleeding. Adrenaline, steroids, heparin, and thrombin do not have the same vasoconstrictive properties as thromboxane.
Question 4 of 5
Which of the following refers to the metabolism of the drug en route from the GUT lumen to the systemic circulation.
Correct Answer: B
Rationale: The first pass effect refers to the metabolism of a drug occurring as it passes from the gastrointestinal tract (GUT lumen) to the liver, before reaching the systemic circulation. This process can significantly reduce the amount of active drug that enters systemic circulation, impacting the drug's overall effectiveness. The first pass effect is an important consideration in pharmacokinetics as it affects the bioavailability of a drug and influences dosing regimens. Options A, C, D, and E do not specifically pertain to the metabolism of a drug en route from the GUT lumen to the systemic circulation as described in the question.
Question 5 of 5
A patient is receiving tetracycline. Which advice should the nurse include when teaching this patient about tetracycline?
Correct Answer: A
Rationale: Tetracycline can cause photosensitivity, increasing the risk of severe sunburn. Patients should be advised to use sunscreen and avoid prolonged sun exposure. Taking antacids with tetracycline is contraindicated, as they can bind to the drug and reduce its absorption. Hearing loss and retinal damage are not associated with tetracycline use. Instead, patients should be monitored for gastrointestinal side effects and advised to take the medication with food if tolerated.