The central dogma concerning the flow of information from genetic material was first introduced by

Correct Answer: B

Rationale: The central dogma of molecular biology, which describes the flow of genetic information from DNA to RNA to proteins, was first proposed by Francis Crick. Crick, along with James Watson, discovered the structure of DNA in 1953, leading to the understanding of how genetic information is stored and transmitted. Ernst Ruska was a physicist who developed the electron microscope, not related to genetic information flow. Camillo Golgi was an Italian biologist known for the discovery of the Golgi apparatus, not central to the central dogma. Carl Bender is not a prominent figure in the field of molecular biology. In summary, Francis Crick is the correct answer as he played a pivotal role in introducing the central dogma of molecular biology.

Correct Answer: C

Rationale: The correct answer is C: Measles serological test. This is because the clinical presentation of high fever, maculopapular rash, and Filatov-Koplik's spots on the buccal mucosa are classic symptoms of measles. The presence of Filatov-Koplik's spots is highly specific for measles. Performing a measles serological test will help confirm the diagnosis by detecting measles-specific antibodies in the blood. Incorrect choices: A: Mumps serological test - Mumps typically presents with parotitis (swelling of the parotid glands) and not with Filatov-Koplik's spots. B: Enteroviruses serological test - Enteroviruses do not typically cause Filatov-Koplik's spots or the classic triad of symptoms seen in measles. D: Influenza virus serological test - Influenza virus does not cause Filatov-Koplik's spots and the characteristic rash seen

Correct Answer: A

Rationale: The correct answer is A: Neisser. Bacterial capsules can be stained using the Neisser staining method because it specifically targets the capsule, making it visible under a microscope. Neisser staining involves using a combination of acidic and basic dyes to highlight the capsule structure. This method helps differentiate the capsule from the bacterial cell, aiding in the identification and study of capsules. Choices B, C, and D are incorrect because Cleat and Müller staining methods are not commonly used for staining bacterial capsules, and "None of the above" is incorrect as Neisser staining is a valid method for capsule staining.

Correct Answer: C

Rationale: The correct answer is C: ECHO virus infection. ECHO virus is transmitted via the fecal-oral route, meaning the virus is passed from feces to the mouth. This transmission occurs through contaminated food, water, or surfaces. Relapsed fever and spotted fever are generally transmitted by arthropod vectors like ticks. Pertussis, also known as whooping cough, spreads through respiratory droplets. Therefore, the fecal-oral route is not applicable to these diseases.

Correct Answer: D

Rationale: Step 1: Streptococcus pneumoniae is a common cause of community-acquired pneumonia. Step 2: Mycobacterium tuberculosis can lead to tuberculosis, which can manifest as pulmonary tuberculosis. Step 3: Escherichia coli is not typically associated with causing pneumonia. Step 4: Since Streptococcus pneumoniae and Mycobacterium tuberculosis are linked to pneumonia, and Escherichia coli is not, the correct answer is D - All of the above.

Correct Answer: B

Rationale: The correct answer is B: CDC. The Centers for Disease Control and Prevention (CDC) is responsible for establishing hand-washing guidelines in healthcare settings to prevent infections. CDC is a leading authority in public health and provides evidence-based recommendations. OSHA (A) focuses on workplace safety, NIAD (C) is not a recognized organization, and WHO (D) provides global health guidelines but CDC is the primary authority for hand hygiene in the US healthcare system.

Correct Answer: A

Rationale: The correct answer is A: Streptococcus pneumoniae. The presence of Gram-positive cocci in pairs indicates a bacterial morphology consistent with Streptococcus pneumoniae, a common cause of pneumonia. This bacterium is known to appear in pairs or short chains on Gram stain. Staphylococcus aureus (B) typically presents as clusters of Gram-positive cocci, Neisseria meningitidis (C) is a Gram-negative diplococcus, and Klebsiella pneumoniae (D) is a Gram-negative rod, making them less likely causative agents in this scenario.

Correct Answer: D

Rationale: The correct answer is D: stereomicroscopes. These types of microscopes, also known as dissecting microscopes, are designed for observing larger objects like insects or worms. They have a lower magnification power compared to electron microscopes (A), which are used to observe smaller objects at a much higher resolution. Dark-field microscopes (B) are used for observing live and unstained samples with high contrast, not specifically for larger objects. Fluorescence microscopes (C) are used to observe specimens that fluoresce under specific wavelengths of light, not necessarily for large objects like insects or worms. Therefore, the most suitable choice for observing fairly large objects like insects or worms is stereomicroscopes.

Correct Answer: A

Rationale: The Burri-Gins staining technique is used to identify capsule formation in bacteria. Capsules are protective layers around bacteria that can be visualized using this staining method. Capsules are important virulence factors for pathogens like Yersinia pestis, the causative agent of plague. This technique helps in differentiating encapsulated bacteria from non-encapsulated ones. Spore formation (B), acid resistance (C), and alkali resistance (D) are not properties that can be identified using the Burri-Gins technique, making them incorrect choices.