ATI RN
microbiology chapter 1 test bank Questions
Question 1 of 5
The central dogma concerning the flow of information from genetic material was first introduced by
Correct Answer: B
Rationale: The central dogma of molecular biology, which describes the flow of genetic information from DNA to RNA to proteins, was first proposed by Francis Crick. Crick, along with James Watson, discovered the structure of DNA in 1953, leading to the understanding of how genetic information is stored and transmitted. Ernst Ruska was a physicist who developed the electron microscope, not related to genetic information flow. Camillo Golgi was an Italian biologist known for the discovery of the Golgi apparatus, not central to the central dogma. Carl Bender is not a prominent figure in the field of molecular biology. In summary, Francis Crick is the correct answer as he played a pivotal role in introducing the central dogma of molecular biology.
Question 2 of 5
Hand-washing guidelines have been established by
Correct Answer: B
Rationale: The correct answer is B: CDC. The Centers for Disease Control and Prevention (CDC) is responsible for establishing hand-washing guidelines in healthcare settings to prevent infections. CDC is a leading authority in public health and provides evidence-based recommendations. OSHA (A) focuses on workplace safety, NIAD (C) is not a recognized organization, and WHO (D) provides global health guidelines but CDC is the primary authority for hand hygiene in the US healthcare system.
Question 3 of 5
48 hours after performing tuberculin test (Mantoux test) to a child a 10 mm papule appeared on the spot of tuberculin introduction. What hypersensitivity mechanism underlies these changes?
Correct Answer: D
Rationale: The correct answer is D: Granulomatosis. The appearance of a 10 mm papule 48 hours after the Mantoux test indicates a delayed-type hypersensitivity reaction, which is characteristic of granulomatosis. This type of reaction involves activation of macrophages and T cells, leading to the formation of granulomas. Granulomas are organized collections of immune cells that wall off the antigen, in this case, the tuberculin antigen. A, B, and C are incorrect: A: Cellular cytotoxicity involves the destruction of target cells by immune cells such as cytotoxic T cells or natural killer cells. This mechanism is not associated with the delayed-type hypersensitivity reaction seen in granulomatosis. B: Anaphylaxis is a rapid and severe allergic reaction involving IgE-mediated release of histamine and other inflammatory mediators. This is not the mechanism underlying the delayed-type hypersensitivity reaction in the Mantoux test. C: Antibody-dependent cytotoxic
Question 4 of 5
In a maternity hospital a newborn should receive vaccination against tuberculosis. What vaccine should be chosen?
Correct Answer: A
Rationale: The correct answer is A: BCG vaccine. Step 1: BCG vaccine is specifically designed to protect against tuberculosis, making it the appropriate choice for newborns. Step 2: STI vaccine is for sexually transmitted infections, not tuberculosis. Step 3: EV vaccine is not a recognized vaccine. Step 4: DPT vaccine protects against diphtheria, pertussis, and tetanus, not tuberculosis. In summary, BCG vaccine is the correct choice as it targets tuberculosis specifically, while the other options are designed for different purposes.
Question 5 of 5
The laboratory for especially dangerous infections conducts microscopic examination of pathological material from a patient with suspected plague. The sample was stained by Burri-Gins technique. What property of the causative agent can be identified by this technique?
Correct Answer: A
Rationale: The Burri-Gins staining technique is used to identify capsule formation in bacteria. Capsules are protective layers around bacteria that can be visualized using this staining method. Capsules are important virulence factors for pathogens like Yersinia pestis, the causative agent of plague. This technique helps in differentiating encapsulated bacteria from non-encapsulated ones. Spore formation (B), acid resistance (C), and alkali resistance (D) are not properties that can be identified using the Burri-Gins technique, making them incorrect choices.