The central dogma concerning the flow of information from genetic material was first introduced by

Correct Answer: B

Rationale: The central dogma of molecular biology, which describes the flow of genetic information from DNA to RNA to proteins, was first proposed by Francis Crick. Crick, along with James Watson, discovered the structure of DNA in 1953, leading to the understanding of how genetic information is stored and transmitted. Ernst Ruska was a physicist who developed the electron microscope, not related to genetic information flow. Camillo Golgi was an Italian biologist known for the discovery of the Golgi apparatus, not central to the central dogma. Carl Bender is not a prominent figure in the field of molecular biology. In summary, Francis Crick is the correct answer as he played a pivotal role in introducing the central dogma of molecular biology.

Correct Answer: C

Rationale: Rationale: 1. Shigella invades and multiplies within the intestinal epithelial cells, causing inflammation and tissue damage locally. 2. It does not spread systemically, unlike Yersinia enterocolitica and Listeria monocytogenes. 3. Shigella's pathogenesis is focused on invasion and multiplication at the site of infection, leading to symptoms of dysentery. 4. Yersinia enterocolitica and Listeria monocytogenes can disseminate beyond the gastrointestinal tract, causing systemic infections. Summary: - A (Yersinia enterocolitica) and B (Listeria monocytogenes) are incorrect as they can generalize the infectious process. - C (Shigella) is correct as it mainly involves invasion and intraepithelial multiplication without spreading systemically.

Correct Answer: D

Rationale: The correct answer is D because it encompasses the true statements regarding the laboratory diagnosis of urinary tract infections. A: Bacteriuria of less than 10^5 can be significant in treated patients due to the development of antibiotic resistance. B: Staphylococcus aureus, Salmonella typhi, and Mycobacterium tuberculosis may be significant regardless of quantity due to their pathogenic nature. C: Leukocyturia indicates inflammation, and even a lower number of leukocytes can be clinically significant. Therefore, option D covers all these aspects making it the correct choice.

Correct Answer: D

Rationale: The correct answer is D: All of the above. HIV can be transmitted from mother to child during delivery through mixing of blood, during pregnancy through the placenta, and via breastmilk during lactation. Each mode of transmission carries a risk of HIV transmission to the child due to the presence of the virus in the mother's blood and bodily fluids. It is important to note that all three modes contribute to the risk of mother-to-child transmission of HIV, and preventive measures should be taken to reduce this risk. Option A, during delivery through mixing of blood, is correct as HIV can be transmitted through exposure to infected blood during childbirth. Option B, during pregnancy through placenta, is also correct as the virus can cross the placenta and infect the fetus. Option C, via breastmilk during lactation, is correct as HIV can be present in breastmilk and transmitted to the child through breastfeeding. Therefore, the preferred mode of transmission of HIV from a mother to a child

Correct Answer: B

Rationale: The correct answer is B: Typhoid fever, Brucellosis. Both Typhoid fever and Brucellosis are bacterial infections that can lead to bacteremia, the presence of bacteria in the bloodstream. In Typhoid fever, the causative agent Salmonella typhi can enter the bloodstream, causing bacteremia. Similarly, Brucellosis, caused by Brucella species, can also result in bacteremia. Choice A is incorrect because bacteremia is not typically observed in Diphtheria. Choice C, Cholera, is caused by a toxin-producing bacterium and does not usually lead to bacteremia. Choice D, Dysentery, is a condition characterized by bloody diarrhea and is primarily caused by parasites or bacteria that typically do not lead to bacteremia.

Correct Answer: A

Rationale: The correct answer is A: Pertussis bacillus. The symptoms described - elevated temperature and typical cough - are indicative of whooping cough, caused by Bordetella pertussis. By inoculating mucus from the nasopharynx on agar, the doctor is trying to isolate the causative agent, which is likely to be Pertussis bacillus. Summary of other choices: B: Pfeiffer's bacillus (Haemophilus influenzae): Unlikely as symptoms do not match. C: Listeria: Unlikely as it typically causes foodborne illness, not respiratory infections. D: Klebsiella: Unlikely as it is more commonly associated with pneumonia in immunocompromised individuals.

Correct Answer: D

Rationale: The correct answer is D: commensalism. In commensalism, one organism benefits while the other is neither helped nor harmed. In this relationship, the waste product of one organism serves as a nutrient source for another without affecting the first organism. Mutualism (A) involves both organisms benefiting, competition (B) involves a struggle for resources, and synergism (C) involves cooperative interactions. Commensalism is the only choice where one organism benefits from the waste product of another without any impact on the producer.

Correct Answer:

Rationale: Correct Answer: C: opportunists Rationale: 1. Opportunistic microorganisms cause infections only when the host's immune system is compromised. 2. They are typically harmless in healthy individuals but can become pathogenic in weakened hosts. 3. Saprophytic microorganisms are environmental decomposers, not inherently pathogenic. 4. Facultative pathogens can cause disease in both healthy and compromised hosts. 5. Obligate pathogens always cause disease regardless of the host's condition. Summary: A: Facultative pathogens can cause disease in healthy hosts. B: Saprophytes are not inherently pathogenic. D: Obligate pathogens always cause disease.

Correct Answer: C

Rationale: The correct answer is C (60 years) because as individuals age, their immune system weakens, making them more susceptible to infectious diseases. Around the age of 60, people are more likely to succumb to infections, leading to a higher mortality rate. Choices A, B, and D are incorrect because they are younger ages, and the likelihood of infectious diseases causing a significant proportion of deaths increases with age.