ATI RN
microbiology basic and clinical principles test bank Questions
Question 1 of 5
The cell envelope of Gram-negative bacteria is composed of:
Correct Answer: A
Rationale: The correct answer is A because Gram-negative bacteria have a unique cell envelope structure consisting of a cytoplasmic membrane, a peptidoglycan layer, and an outer membrane. The cytoplasmic membrane is the innermost layer that separates the cytoplasm from the external environment. The peptidoglycan layer provides structural support to the cell. The outer membrane acts as an additional protective barrier and contains lipopolysaccharides. Choice B is incorrect because Gram-negative bacteria have an outer membrane in addition to the cytoplasmic membrane and peptidoglycan layer. Choice C is incorrect because Gram-negative bacteria have more than just a peptidoglycan layer in their cell envelope. Choice D is incorrect as the cell envelope of Gram-negative bacteria does have specific components.
Question 2 of 5
Formic acid is a fermentation product of
Correct Answer: D
Rationale: Step 1: Formic acid is produced during fermentation by Actinomyces. Step 2: Actinomyces are known to produce organic acids like formic acid through fermentation. Step 3: Other choices like Streptococcus, Klebsiella, and Clostridium are not typically associated with formic acid production. Step 4: Actinomyces is the most likely candidate based on its fermentation capabilities. Summary: Actinomyces is the correct answer because it is known to produce formic acid during fermentation, while the other choices lack this specific metabolic function.
Question 3 of 5
A 30-year-old patient complains about having abdominal pain and diarrhea for five days; body temperature rise up to 37, 5oC along with chills. The day before a patient had been in a forest and drunk from an open water reservoir. Laboratory analyses enabled to make the following diagnosis: amebic dysentery. What is the drug of choice for its treatment?
Correct Answer: A
Rationale: The correct answer is A: Metronidazole. Rationale: 1. Metronidazole is the drug of choice for amebic dysentery due to its effectiveness against the causative agent, Entamoeba histolytica. 2. Metronidazole has good tissue penetration and is able to reach the site of infection in the gut. 3. It is a bactericidal drug that acts by disrupting the DNA structure of the parasite. 4. Metronidazole is well-absorbed orally and has minimal side effects. Summary of other choices: B: Furazolidonum - Not the drug of choice for amebic dysentery. It is primarily used for treating bacterial diarrhea. C: Levomycetin - Not effective against Entamoeba histolytica and not recommended for amebic dysentery. D: Phthalazol - Not commonly used for amebic dysentery treatment. Metronidazole is preferred due
Question 4 of 5
A 28-year-old patient was hospitalized with preliminary diagnosis "influenza". Roseolous-petechial rash appeared on the 5th day of disease on the trunk. The temperature is 41oC. Hyperemia of face, reddening of scleras, tremor of tongue, tachycardia, splenomegaly are present. What is the most likely diagnosis?
Correct Answer: A
Rationale: The most likely diagnosis is Epidemic typhus (Choice A) based on the symptoms described. The presence of roseolous-petechial rash, high fever (41oC), hyperemia of face, reddening of scleras, tremor of the tongue, tachycardia, and splenomegaly are classic signs of epidemic typhus. The rash typically appears around the 5th day of the disease. Summary: - B: Measles typically presents with a maculopapular rash starting on the face and spreading downward. It doesn't usually present with tremor of the tongue or splenomegaly. - C: Alcohol delirium is characterized by confusion, disorientation, and hallucinations due to alcohol consumption. It doesn't match the symptoms described. - D: Leptospirosis presents with fever, muscle pain, and conjunctival suffusion. It doesn't typically present with the specific rash and trem
Question 5 of 5
During latency, HSV1 exists in what form:
Correct Answer: B
Rationale: During latency, HSV1 exists as episomes in neurons. This is because HSV1 establishes a lifelong latent infection in sensory neurons, where the viral genome remains as a circular episome in the nucleus. This form allows the virus to persist in a dormant state, avoiding detection by the immune system. Choice A is incorrect as HSV1 does not integrate into the host chromosome. Choice C is incorrect as latency is a well-documented phenomenon for HSV1. Choice D is incorrect as the correct answer is B.
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