ATI RN
mastering microbiology test bank Questions
Question 1 of 5
The causative agent of the disease gas gangrene Clostridium perfringens is:
Correct Answer: C
Rationale: The correct answer is C because Clostridium perfringens is a Gram-positive rod-shaped bacterium, which matches the description provided. It is motile and peritrichous (having flagella all over the surface) without a capsule. This bacterium is known to cause gas gangrene due to its ability to produce toxins that destroy tissue. Choice A is incorrect because Clostridium perfringens is Gram-positive, not Gram-negative, and it does not have a capsule. Choice B is incorrect because Clostridium perfringens is not motile and does not have flagella all over its surface. Choice D is incorrect because Clostridium perfringens is Gram-positive, not Gram-negative, and it is motile without a capsule.
Question 2 of 5
Which of the following statements about in vitro cultivation of viruses is true?
Correct Answer: B
Rationale: The correct answer is B because viruses can indeed be cultured on hen embryos, cell cultures, and experimental animals in vitro. This method allows for the replication and study of viruses outside the host organism. Option A is incorrect as viral cultivation is possible in laboratory settings. Option C is incorrect because while viruses can be grown on nutrient media, it is not the only method. Option D is incorrect as viruses can be cultured in various types of cell cultures, not just human embryonic ones.
Question 3 of 5
Acute hemorrhagic cystitis may be due to:
Correct Answer: C
Rationale: Rationale for choice C (Adenovirus) being correct: 1. Adenovirus is a common cause of acute hemorrhagic cystitis. 2. Adenovirus infects the bladder epithelium, leading to inflammation and bleeding. 3. Symptoms include hematuria and bladder pain. 4. Diagnosis is confirmed through viral culture or PCR testing. Summary of why other choices are incorrect: A: Parvovirus B19 - More commonly associated with erythema infectiosum (fifth disease) and aplastic anemia. B: CMV - Known to cause congenital infections, mononucleosis, and retinitis, not typically associated with hemorrhagic cystitis. D: Herpesvirus type 2 - Commonly causes genital herpes, but not typically associated with acute hemorrhagic cystitis.
Question 4 of 5
Which of the following is a folate antagonist?
Correct Answer: B
Rationale: The correct answer is B: Trimethoprim. Trimethoprim is a folate antagonist that inhibits dihydrofolate reductase, an enzyme essential for folate metabolism in bacteria. This disrupts bacterial DNA synthesis, leading to bacteriostatic effects. Methyl Penicillin (A) is a beta-lactam antibiotic that interferes with bacterial cell wall synthesis. Vancomycin (C) inhibits cell wall synthesis by binding to D-Ala-D-Ala terminus of cell wall precursors. Gentamicin (D) inhibits bacterial protein synthesis by binding to the 30S subunit of the bacterial ribosome.
Question 5 of 5
Which of the following bacteria are unable to synthesize ATP?
Correct Answer: A
Rationale: The correct answer is A: Chlamydia. Chlamydia lacks the essential enzymes for ATP synthesis and relies on host cell ATP. Enterococci, Rickettsia, and Staphylococci possess the necessary enzymes for ATP synthesis through cellular respiration. Chlamydia's inability to synthesize ATP makes it dependent on the host cell for energy production, distinguishing it from the other bacteria listed.