The causative agent of the disease gas gangrene Clostridium perfringens is:

Correct Answer: C

Rationale: The correct answer is C because Clostridium perfringens is a Gram-positive rod-shaped bacterium, which matches the description provided. It is motile and peritrichous (having flagella all over the surface) without a capsule. This bacterium is known to cause gas gangrene due to its ability to produce toxins that destroy tissue. Choice A is incorrect because Clostridium perfringens is Gram-positive, not Gram-negative, and it does not have a capsule. Choice B is incorrect because Clostridium perfringens is not motile and does not have flagella all over its surface. Choice D is incorrect because Clostridium perfringens is Gram-positive, not Gram-negative, and it is motile without a capsule.

Correct Answer: A

Rationale: The correct answer is A: Mantoux test. The Mantoux test is used to screen for tuberculosis by injecting PPD intradermally. The presence of a delayed hypersensitivity reaction indicates prior exposure to Mycobacterium tuberculosis. The Schick test (B) is used to test for immunity to diphtheria, while the Dick test (C) is used to test for immunity to scarlet fever. Therefore, the correct use of PPD is in the Mantoux test for tuberculosis screening.

Correct Answer: A

Rationale: The correct answer is A: Homemade canned meat. Botulism is caused by the Clostridium botulinum bacteria, which thrives in low-oxygen environments like improperly canned food. Homemade canned meat poses a higher risk of contamination as it may not have been processed correctly, allowing the bacteria to grow and produce toxins. Custard pastry, sour cream, and strawberries are less likely to cause botulism as they are not typically associated with the bacteria unless improperly handled or stored. Homemade canned meat is the most probable cause based on the characteristic symptoms of botulism and the conditions that favor the growth of Clostridium botulinum in canned food.

Correct Answer: B

Rationale: The Gram stain differentiates bacteria based on cell wall structure. It classifies bacteria into Gram-positive (purple) and Gram-negative (pink) based on the presence of peptidoglycan in the cell wall. This method helps in identifying the bacterial species and determining appropriate treatment. Option A (Cell shape) is incorrect because the Gram stain focuses on cell wall composition, not cell shape. Option C (Flagella composition) is incorrect as the Gram stain does not assess flagella. Option D (Nutrient requirements) is incorrect as it does not relate to the purpose of the Gram stain.

Correct Answer: A

Rationale: The correct answer is A: Zielh-Neelsen stain. This stain is specifically used to detect acid-fast bacteria like Mycobacterium tuberculosis, the causative agent of renal tuberculosis. The staining process involves using carbol fuchsin to penetrate the mycolic acid layer of the bacterial cell wall, making it resistant to decolorization with acid-alcohol. This allows the red stained bacteria to be visualized under a microscope. Loeffler stain (B) is used for staining bacteria like diphtheria bacilli, Gram stain (C) is used for bacterial classification based on cell wall properties, and Aujeszky stain (D) is not a recognized staining method for detecting acid-fast bacteria.

Correct Answer: A

Rationale: The correct answer is A: Malaria. The patient's travel history to an endemic area like Tajikistan, along with symptoms of fever with chills, sweating, and hepatosplenomegaly, are classic for malaria. The blood test results show anemia (low RBC and hemoglobin levels), which can occur in malaria due to hemolysis. The presence of eosinophils and lymphocytes are not typical for malaria, but the overall clinical picture fits. Infectious mononucleosis (choice B) typically presents with sore throat, lymphadenopathy, and atypical lymphocytosis, which are not seen in this case. Sepsis (choice C) is characterized by systemic inflammatory response syndrome and organ dysfunction due to infection, which does not align with the symptoms and findings in the case. Typhoid fever (choice D) usually presents with gradual onset of sustained fever, abdominal pain, headache, and constipation, which are not present in this patient

Correct Answer: A

Rationale: The correct answer is A: evade host immune responses. Antigenic variation allows bacteria to change their surface antigens, making it difficult for the host immune system to recognize and attack them effectively. This enhances the bacteria's ability to evade immune responses and establish infection. B: Increase antibiotic susceptibility is incorrect because antigenic variation does not directly impact the susceptibility of bacteria to antibiotics. C: Increase peptidoglycan synthesis is incorrect because antigenic variation is not related to the synthesis of peptidoglycan, which is a major component of the bacterial cell wall. D: Enhance motility is incorrect because antigenic variation does not directly affect the motility of bacteria. In summary, antigenic variation in bacteria primarily serves to help them evade host immune responses, making option A the correct answer.

Correct Answer: C

Rationale: The correct answer is C because Clostridium perfringens is a Gram-positive rod-shaped bacterium, which matches the description provided. It is motile and peritrichous (having flagella all over the surface) without a capsule. This bacterium is known to cause gas gangrene due to its ability to produce toxins that destroy tissue. Choice A is incorrect because Clostridium perfringens is Gram-positive, not Gram-negative, and it does not have a capsule. Choice B is incorrect because Clostridium perfringens is not motile and does not have flagella all over its surface. Choice D is incorrect because Clostridium perfringens is Gram-positive, not Gram-negative, and it is motile without a capsule.

Correct Answer: A

Rationale: Step-by-step rationale for answer A: 1. Pseudomonas aeruginosa is known to cause burn wounds infections due to its ability to survive in moist environments. 2. It can cause severe pneumonia in patients with cystic fibrosis due to its resistance to antibiotics and ability to form biofilms. 3. It is a common cause of nosocomial infections in hospitals due to its ability to colonize medical equipment and surfaces. Summary of other choices: B. Pseudomonas aeruginosa typically does not cause food poisoning, as it is not a common pathogen associated with foodborne illnesses. C. Bacterial pharyngitis is usually caused by Streptococcus pyogenes, not Pseudomonas aeruginosa, making this choice incorrect. D. None of the above is incorrect as Pseudomonas aeruginosa is associated with specific infections mentioned in option A.