The causative agent of the disease gas gangrene Clostridium perfringens is:

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Question 1 of 9

The causative agent of the disease gas gangrene Clostridium perfringens is:

Correct Answer: C

Rationale: The correct answer is C because Clostridium perfringens is a Gram-positive rod-shaped bacterium, which matches the description provided. It is motile and peritrichous (having flagella all over the surface) without a capsule. This bacterium is known to cause gas gangrene due to its ability to produce toxins that destroy tissue. Choice A is incorrect because Clostridium perfringens is Gram-positive, not Gram-negative, and it does not have a capsule. Choice B is incorrect because Clostridium perfringens is not motile and does not have flagella all over its surface. Choice D is incorrect because Clostridium perfringens is Gram-positive, not Gram-negative, and it is motile without a capsule.

Question 2 of 9

Which of the following diseases is transmitted by the fecal–oral route?

Correct Answer: B

Rationale: The correct answer is B: Peptic ulcer. Peptic ulcers are commonly caused by Helicobacter pylori bacteria, which can be transmitted through the fecal-oral route. This means that the bacteria from infected feces can be ingested through contaminated food or water, leading to the development of peptic ulcers in the gastrointestinal tract. Incorrect choices: A: Ehrlichiosis - Ehrlichiosis is a tick-borne disease transmitted through the bite of an infected tick, not through the fecal-oral route. C: Lyme disease - Lyme disease is also transmitted through the bite of an infected tick, specifically the black-legged tick. D: Tularemia - Tularemia is a bacterial disease typically transmitted through insect bites, handling of infected animals, or ingestion of contaminated water, not through the fecal-oral route.

Question 3 of 9

Treponemae are motile because of:

Correct Answer: A

Rationale: The correct answer is A: axial filaments. Treponemae are motile due to their unique structure of axial filaments, also known as endoflagella. These axial filaments are located within the periplasmic space of the organism and are responsible for the corkscrew-like motility of Treponemae. The other choices (B: mans peritrichous filaments, C: single monotrichous filament, D: fimbriae) do not play a role in the motility of Treponemae. Peritrichous filaments and single monotrichous filaments are not present in Treponemae, and fimbriae are primarily involved in adhesion rather than motility.

Question 4 of 9

Adenoviruses have helical capsids:

Correct Answer: B

Rationale: Step 1: Adenoviruses are known to have icosahedral capsids, not helical. Step 2: Helical capsids are typically found in viruses like tobacco mosaic virus. Step 3: Therefore, the statement that adenoviruses have helical capsids is FALSE. Summary: A is incorrect as adenoviruses do not have helical capsids. C is incorrect as there is no situation where adenoviruses have helical capsids. D is incorrect as there is a clear correct answer, which is B.

Question 5 of 9

On the 5th day after a surgery for colon injury a patient complains of bursting pain in the postoperative wound, weakness, drowsiness, headache, fever up to 40oC. Objectively: the skin around the wound is swollen, there is gas crepitation. The wound discharges are scarce foul-smelling, of dark-gray color. What is the most likely diagnosis?

Correct Answer: A

Rationale: The correct answer is A: Anaerobic clostridial wound infection. The symptoms and signs described (bursting pain, weakness, drowsiness, fever, swollen skin, gas crepitation, foul-smelling dark-gray discharge) are classic for gas gangrene, caused by Clostridium perfringens. Gas gangrene is an anaerobic infection that thrives in devitalized tissue, such as postoperative wounds. The gas crepitation is due to gas production by the bacteria. Abscess (B) typically presents with localized swelling and fluctuance, not gas crepitation. Postoperative wound infection (C) may present with redness, warmth, and increased wound discharge but not the specific features mentioned. Erysipelas (D) is a superficial bacterial skin infection, typically caused by Streptococcus pyogenes, presenting with well-defined raised borders and redness.

Question 6 of 9

Which of the following is a feature of Gram-negative bacteria?

Correct Answer: B

Rationale: The correct answer is B: Outer membrane with lipopolysaccharides. Gram-negative bacteria have an outer membrane containing lipopolysaccharides (LPS), which are important in pathogenesis and immune response. This feature is unique to Gram-negative bacteria, distinguishing them from Gram-positive bacteria (choice A). Teichoic acids (choice C) are found in the cell walls of Gram-positive bacteria, not Gram-negative. The statement in choice D, absence of a cell wall, is incorrect as all bacteria have a cell wall, although the composition may vary between Gram-negative and Gram-positive bacteria.

Question 7 of 9

Which of the following is a folate antagonist?

Correct Answer: B

Rationale: The correct answer is B: Trimethoprim. Trimethoprim is a folate antagonist that inhibits dihydrofolate reductase, an enzyme essential for folate metabolism in bacteria. This disrupts bacterial DNA synthesis, leading to bacteriostatic effects. Methyl Penicillin (A) is a beta-lactam antibiotic that interferes with bacterial cell wall synthesis. Vancomycin (C) inhibits cell wall synthesis by binding to D-Ala-D-Ala terminus of cell wall precursors. Gentamicin (D) inhibits bacterial protein synthesis by binding to the 30S subunit of the bacterial ribosome.

Question 8 of 9

Algae that contain agar in their cell walls belong to:

Correct Answer: B

Rationale: The correct answer is B: Rhodophyta. Rhodophyta is the phylum of red algae, which are known to contain agar in their cell walls. Agar is a gelatinous substance derived from these algae. Chrysophyta (A), Chlorophyta (C), and Phaeophyta (D) do not typically contain agar in their cell walls. Chrysophyta includes diatoms, Chlorophyta includes green algae, and Phaeophyta includes brown algae, none of which are known for agar production. Therefore, Rhodophyta is the correct choice based on the presence of agar in their cell walls.

Question 9 of 9

Which of the following is a general-purpose medium?

Correct Answer: A

Rationale: The correct answer is A: Tryptic soy agar is a general-purpose medium suitable for cultivating a wide range of microorganisms. It provides essential nutrients for growth without inhibiting specific types of bacteria. Blood agar (B), Mannitol salt agar (C), and MacConkey agar (D) are selective or differential media designed to promote the growth of specific types of bacteria or differentiate between different bacterial species. Therefore, they are not considered general-purpose mediums.

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