The beta subunit of human chorionic gonadotropin (HCG) is a useful surface marker in some malignant germ cell tumors (GCTs); it is secreted by syncytiotrophoblasts. In which of the following GCTs this surface marker is characteristically elevated?

Correct Answer: D

Rationale: Embryonal carcinoma is strongly associated with elevated beta-HCG levels.

Correct Answer: A

Rationale: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an inborn error of metabolism that leads to the premature destruction of red blood cells (hemolysis). G6PD is an enzyme responsible for protecting red blood cells from oxidative damage. In individuals with G6PD deficiency, the red blood cells are more susceptible to oxidative stress, leading to their destruction and resulting in hemolytic anemia. This condition is commonly triggered by certain medications, infections, or dietary factors that cause oxidative stress, leading to hemolysis. Homocystinuria, Phenylketonuria, and Celiac Disease are metabolic disorders that do not typically result in the premature destruction of red blood cells.

Correct Answer: B

Rationale: A healthy newborn's respirations are typically irregular, abdominal, with a rate of 30-60 per minute, and tend to be shallow. Newborns have immature respiratory centers in their brain, leading to irregular breathing patterns compared to adults. Their breathing is usually abdominal due to their diaphragmatic breathing pattern. The normal respiratory rate for a newborn can fluctuate between 30-60 breaths per minute, with shallow breathing being characteristic of their physiology. Regular shallow breathing with occasional periods of apnea is considered normal in newborns and should not be a cause for concern.

Correct Answer: A

Rationale: A biopsy is a diagnostic procedure that involves the removal of a small sample of tissue or cells from the body for examination under a microscope. This is done to determine the presence of abnormal or malignant cells, which can indicate the presence of cancer or other diseases. Biopsies are often performed when there is a suspicion of cancer based on imaging studies or other clinical findings. Detecting malignant cells through a biopsy is crucial for accurate diagnosis and appropriate treatment planning. Early detection of cancer through biopsy can significantly improve the prognosis and survival rates of patients.

Correct Answer: A

Rationale: Orthopnea is a common symptom of congestive heart failure. It is defined as difficulty in breathing when lying flat, which improves when sitting up or standing. This occurs due to the redistribution of blood in the body when changing positions. As fluid accumulates in the lungs in congestive heart failure, lying down increases pressure on the chest and impairs breathing. Therefore, orthopnea is a significant assessment finding that would suggest to the home health nurse that the patient is developing congestive heart failure. Fever, weight loss, and calf pain are not typically associated with congestive heart failure.