The best approach to therapy for patients with homozygous familial hypercholesterolemia is

Correct Answer: B

Rationale: LDL apheresis is the most effective therapy for homozygous FH to lower cholesterol.

Correct Answer: A

Rationale: McArdle (type V) causes muscle cramps and exercise intolerance.

Correct Answer: D

Rationale: DKA includes hyperglycemia (A), ketonemia (B), ketonuria (C), and low HCO₃ (E), but venous pH is typically <7.30, not necessarily <7.20 (D), which is more severe.

Correct Answer: C

Rationale: The pituitary sits in the sella turcica of the sphenoid bone (C).

Correct Answer: D

Rationale: Hyperglycemia (D) does not directly stimulate VP; it causes osmotic diuresis. Others (A-C, E) are known triggers.