ATI RN
Genitourinary System Quizlet Questions
Question 1 of 5
The antiviral action of amantadine is exerted through: *
Correct Answer: C
Rationale: The correct answer is C: Interaction with the viral M2 protein. Amantadine blocks the M2 ion channel of the influenza A virus, preventing the release of viral RNA into the host cell. This inhibits the viral replication process. Option A is incorrect as amantadine does not target viral protease enzymes. Option B is incorrect as amantadine does not inhibit viral RNA-mediated DNA synthesis, which is a process specific to retroviruses. Option D is incorrect as amantadine does not interact with virus-directed thymidine kinase, which is involved in the activation of certain antiviral medications.
Question 2 of 5
Which statement best describes Zidovudine: *
Correct Answer: C
Rationale: Rationale for Correct Answer (C): 1. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI) used in the treatment of HIV. 2. Zidovudine is indeed converted by cellular enzymes to its active form, zidovudine diphosphate. 3. Zidovudine diphosphate inhibits the reverse transcriptase enzyme, preventing viral DNA replication in HIV-infected cells. 4. This mechanism of action is crucial in reducing viral load and slowing disease progression in HIV patients. Summary of Incorrect Choices: A: Incorrect. While Zidovudine is used in combination therapy for HIV, it is not typically an alternative initial treatment. B: Incorrect. Zidovudine can be used to prevent mother-to-child transmission of HIV, but it is not its primary indication. D: Incorrect. Peripheral neuropathy is not a specific adverse reaction to Zidovudine; rather, it is more commonly associated with
Question 3 of 5
The following topical antifungal drugs include all EXCEPT: *
Correct Answer: B
Rationale: The correct answer is B: Crotamiton. Crotamiton is not an antifungal drug; it is actually a scabicide and antipruritic agent used to treat scabies and itching. A: Tolnaftate is an antifungal commonly used to treat fungal skin infections like athlete's foot. C: Terbinafine is an antifungal medication used to treat fungal infections of the skin and nails. D: Ciclopirox is an antifungal used to treat fungal infections of the nails and skin.
Question 4 of 5
A patient was treated with digoxin and he develop signs and symptoms of * digoxin toxicity caused by furosemide therapy. What did the diuretic most likely do to precipitate the digoxin toxicityy?
Correct Answer: C
Rationale: The correct answer is C: caused by hypokalemia. Furosemide, a loop diuretic, can lead to potassium loss (hypokalemia), which can exacerbate digoxin toxicity. Low potassium levels increase the risk of digoxin binding more strongly to cardiac tissue, leading to toxicity symptoms. Hypocalcemia (A) and hyponatremia (B) are not directly related to digoxin toxicity, making them incorrect choices. Choice D is incorrect as hypokalemia is a known risk factor for digoxin toxicity.
Question 5 of 5
A 75 year old man is suffering from benign prostatic hypertrophy and is being * treated with terazosin. Which of the following adverse reaction would be expected taking this drug?
Correct Answer: B
Rationale: The correct answer is B: Orthostatic hypotension. Terazosin is an alpha-1 blocker commonly used to treat BPH. It can cause vasodilation, leading to a drop in blood pressure, especially when standing up suddenly, resulting in orthostatic hypotension. This is because terazosin relaxes smooth muscle in blood vessels, causing dilation and blood pooling in the extremities. Erectile dysfunction (A) is not a common side effect of terazosin. GI distress (C) is less likely because terazosin does not directly affect the gastrointestinal system. Gynecomastia (D) is not a typical side effect of terazosin since it does not impact hormone levels significantly.