The antigen receptor on a T cell recognizes a degraded fragment of a protein (i.e., a peptide) bound to a specialized cell surface peptide-binding receptor called an MHC molecule. One key aspect of this system is that the peptides displayed on MHC molecules can be derived from intracellular proteins. This mode of antigen recognition is particularly important in allowing the adaptive immune response to detect infections by:

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Question 1 of 5

The antigen receptor on a T cell recognizes a degraded fragment of a protein (i.e., a peptide) bound to a specialized cell surface peptide-binding receptor called an MHC molecule. One key aspect of this system is that the peptides displayed on MHC molecules can be derived from intracellular proteins. This mode of antigen recognition is particularly important in allowing the adaptive immune response to detect infections by:

Correct Answer: B

Rationale: MHC presentation of intracellular peptides detects viruses/protozoa ; extracellular pathogens (C, D) or helminths are less MHC-dependent.

Question 2 of 5

In rare instances, B cells can be found that have two immunoglobulin light chain alleles, both of which are rearranged in frame, and can encode functional light chain proteins. Yet, on the surface of the B cell, only one of the two light chain proteins is detected in the membrane-bound immunoglobulin receptor. The reason these rare cells have two functional light chain rearrangements but only express one of the two light chains as part of the B-cell receptor is:

Correct Answer: B

Rationale: Allelic exclusion ensures one light chain pairs with heavy chain ; pseudogenes , transcription , or RAG don't explain this.

Question 3 of 5

the characteristic of blood types AB is

Correct Answer: A

Rationale: Blood type AB is a universal recipient (general receptor) because it has no antibodies against A, B, or Rh antigens, but it is not a universal donor.

Question 4 of 5

Passive immunity depends upon

Correct Answer: B

Rationale: Passive immunity involves receiving pre-formed antibodies from another source, not self-production or cell transfer.

Question 5 of 5

HIV is a virus that is particularly difficult to eradicate

Correct Answer: C

Rationale: HIV's high mutation rate creates drug-resistant strains, complicating eradication, not its RNA genome, rare mutation, or size.

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