ATI RN
ATI Pharmacology Practice A 2023 Questions
Question 1 of 5
the antidote for Warfarin is?
Correct Answer: B
Rationale: Warfarin is an oral anticoagulant that works by inhibiting the synthesis of vitamin K-dependent clotting factors in the liver. Therefore, the antidote for Warfarin overdose or to reverse its effects is vitamin K. Vitamin K helps in replenishing the depleted vitamin K-dependent clotting factors, allowing the blood to clot normally again. Administering vitamin K helps in reversing the anticoagulant effects of Warfarin, preventing excessive bleeding or hemorrhage.
Question 2 of 5
The goal of androgen therapy in men is to
Correct Answer: D
Rationale: Androgen therapy in men, typically testosterone replacement, aims to boost libido and treat erectile dysfunction by restoring normal androgen levels, countering hypogonadism's effects like reduced sexual drive. Decreasing libido contradicts its purpose, as low testosterone already dims desire. It doesn't release follicle-stimulating hormone (FSH)-exogenous androgens may suppress FSH and LH via feedback inhibition. Increasing luteinizing hormone (LH) isn't the goal; therapy bypasses LH by directly providing testosterone. Raising libido aligns with correcting symptoms of androgen deficiency, improving quality of life and sexual function, a primary clinical indication supported by its action on androgen receptors in sexual tissues.
Question 3 of 5
A mother asks the nurse when she should give her child cough medicine. What is the best response by the nurse?
Correct Answer: D
Rationale: Cough suppressants relieve dry, disruptive coughs , aiding rest. Green secretions need clearance, fever signals illness, and bronchitis may require expectorants. D targets appropriate use, making it the best response.
Question 4 of 5
A neighbor tells nurse Maureen he has to have surgery and is reluctant to have any blood product transfusions because of a fear of contracting an infection. He asks the nurse what are his options. The nurse teaches the person that the safest blood product is:
Correct Answer: C
Rationale: An autologous blood product is the safest option for the neighbor who is reluctant to have blood transfusions due to a fear of contracting an infection. Autologous blood is blood that is donated by the patient themselves prior to surgery. This type of blood product eliminates the risk of transmitting infections from other donors, as the blood comes from the patient's own body. It is considered the safest option for those concerned about infection transmission during blood transfusions.
Question 5 of 5
Which of the following agents if taken in overdose by a depressed patient is most likely to result in a fatal outcome?
Correct Answer: A
Rationale: Overdose fatality depends on toxicity and mechanism. Amitriptyline, a tricyclic antidepressant (TCA), blocks sodium channels and muscarinic receptors, causing lethal arrhythmias, seizures, and anticholinergic effects (LD50 ~13 mg/kg), making it highly fatal. Fluoxetine, fluvoxamine, paroxetine, and citalopram, all SSRIs, primarily cause serotonin syndrome or seizures, but lethality is lower (e.g., citalopram's QT risk is less immediate). TCAs' cardiotoxicity far exceeds SSRIs', driving amitriptyline's higher fatality rate, a critical factor in prescribing for depression with suicide risk.