ATI RN
ATI Pharmacology Practice Exam B Questions
Question 1 of 5
the antidote for Warfarin is?
Correct Answer: B
Rationale: Warfarin is an anticoagulant medication that works by inhibiting the body's ability to use vitamin K to form clotting factors. In cases of excessive anticoagulation or bleeding due to Warfarin, the antidote is vitamin K. Vitamin K helps the body produce clotting factors, thereby reversing the effects of Warfarin and promoting the blood to clot normally. Other medications like Narcan, Glucagon, and Vitamin B do not have a direct antidote effect for Warfarin toxicity.
Question 2 of 5
Which of the following is NOT a therapeutic effect of Montelukast?
Correct Answer: D
Rationale: Montelukast is a medication commonly used to treat asthma and allergic rhinitis. Its therapeutic effects include decreased frequency and severity of acute asthma attacks, decreased severity of allergic rhinitis, and decreased attacks of exercise-induced bronchoconstriction. However, Montelukast is not associated with treating anxiety attacks. Anxiety is a mental health condition that is typically managed with appropriate therapy and medication specifically designed for anxiety disorders.
Question 3 of 5
A drug that has both affinity and intrinsic activity
Correct Answer: D
Rationale: A drug that has both affinity and intrinsic activity is known as a partial agonist. Affinity refers to the drug's ability to bind to a receptor, while intrinsic activity is the drug's ability to activate the receptor and produce a response. A partial agonist binds to the receptor with affinity but only activates the receptor to a partial extent compared to a full agonist. This results in a less potent response compared to a full agonist but also blocks the full agonist's effects, making it act as an antagonist in the presence of a full agonist. In summary, a drug that has both affinity and intrinsic activity is classified as a partial agonist because it binds to the receptor and activates it but to a lesser extent than a full agonist.
Question 4 of 5
The pharmacological property of aspirin comes from its ability to inhibit the synthesis of :
Correct Answer: A
Rationale: Aspirin exerts its pharmacological effects by inhibiting the synthesis of eicosanoids. Eicosanoids are signaling molecules that play a key role in inflammation, pain, and fever. Specifically, aspirin inhibits the enzyme cyclooxygenase (COX), which is crucial for the production of prostaglandins from arachidonic acid. By blocking COX, aspirin reduces the formation of pro-inflammatory prostaglandins, ultimately leading to its anti-inflammatory, analgesic, and antipyretic effects. This mechanism also accounts for aspirin's ability to inhibit platelet aggregation, which is why it is commonly used as an antithrombotic agent.
Question 5 of 5
The nurse assumes care of a patient in the post-anesthesia care unit (PACU). The patient had abdominal surgery and is receiving intravenous morphine sulfate for pain. The patient is asleep and has not voided since prior to surgery. The nurse assesses a respiratory rate of 10 breaths per minute and notes hypoactive bowel sounds. The nurse will contact the surgeon primarily to report which condition?
Correct Answer: B
Rationale: The most critical condition that the nurse should report to the surgeon in this scenario is respiratory depression. Respiratory depression is a potential side effect of opioid medications such as morphine sulfate. It is characterized by a decreased respiratory rate, which in this case, is 10 breaths per minute, indicating inadequate ventilation. Respiratory depression can lead to hypoxia and respiratory arrest if not promptly addressed. The nurse should prioritize notifying the surgeon to ensure immediate intervention and appropriate monitoring to prevent further complications for the patient. While the other conditions (paralytic ileus, somnolence, and urinary retention) are also relevant to the patient's care, respiratory depression poses the most immediate threat to the patient's safety and requires urgent attention.