The antidiabetic agent most likely to cause lactic acidosis is

Questions 16

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Diabetes drugs Questions

Question 1 of 4

The antidiabetic agent most likely to cause lactic acidosis is

Correct Answer: B

Rationale: Phenformin has a higher risk of lactic acidosis than metformin, leading to its withdrawal in many regions.

Question 2 of 4

The agent with negligible mineralocorticoid effect is

Correct Answer: B

Rationale: Betamethasone has minimal mineralocorticoid activity, unlike fludrocortisone (strong) or cortisol.

Question 3 of 4

A diabetic on oral hypoglycaemic drug chlorpropamide, suffered from enteric fever and was prescribed chloramphenicol. He developed severe hypoglycaemia. This is because

Correct Answer: D

Rationale: Chloramphenicol inhibits CYP enzymes, slowing chlorpropamide metabolism and prolonging its hypoglycemic effect.

Question 4 of 4

Diuretic effective in diabetes insipidus is

Correct Answer: A

Rationale: Thiazides paradoxically reduce urine volume in diabetes insipidus by enhancing proximal reabsorption.

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