ATI RN
Chapter 15 The Lymphatic System and Immunity Review Questions Questions
Question 1 of 5
The addition and subtraction of nucleotides at the junctions between V, D, and J gene segments creates antibody proteins with wide variations in the numbers of amino acids in their CDR3 regions. This variability in CDR3 length is important as:
Correct Answer: A
Rationale: CDR3 length variability it doesn't cross placenta ; diversity is broader, not just CDR3 , or affinity .
Question 2 of 5
Which of the following cell types is responsible for the humoral immune response?
Correct Answer: A
Rationale: B cells produce antibodies in the humoral immune response, targeting extracellular pathogens, unlike neutrophils, NK cells, or macrophages.
Question 3 of 5
Why has it been so difficult for researchers to develop effective antivirals for HIV?
Correct Answer: B
Rationale: HIV's rapid mutation rate hinders antiviral development, more than its replication strategy, T cell damage, or transmission mode.
Question 4 of 5
From the options below, which pattern recognition receptor (PRR) gene family is expressed by innate immune cells?
Correct Answer: D
Rationale: Innate immune cells express NLRs (cytosolic), RLRs (viral RNA), and TLRs (surface/cytosolic), making all options correct.
Question 5 of 5
Complete the following sentence. The most common antibody isotype found in serum, with roles in opsonisation, complement activation and ADCC as well as neonatal immunity is.....
Correct Answer: C
Rationale: IgG, the most abundant in serum, performs opsonization, complement activation, ADCC, and crosses the placenta for neonatal immunity.