ATI RN
Pediatric Immunization Practice Questions Questions
Question 1 of 5
The adaptive immune system develops from stem cells originating in the
Correct Answer: B
Rationale: Adaptive immunity arises from stem cells in the fetal liver and bone marrow.
Question 2 of 5
The interaction of which molecule on the membrane of cells with its ligand signals apoptosis?
Correct Answer: D
Rationale: Fas (CD95) binding to FasL triggers apoptosis, critical in immune regulation.
Question 3 of 5
The complement system plays a key role in the host defense process. Which of the following components of this system is the most important in chemotaxis?
Correct Answer: D
Rationale: C5a is the most potent complement-derived chemoattractant for neutrophils.
Question 4 of 5
Digeorge syndrome is known to increase likelihood of infection of some microbes, why is that?
Correct Answer: B
Rationale: DiGeorge syndrome impairs thymus development, reducing T cell production.
Question 5 of 5
A 17-month-old girl presented with history of recurrent attacks of pneumonia since the age of 8 months. You suspect a predominant B-cell defect. Of the following, the BEST simple initial screening test is
Correct Answer: D
Rationale: Isohemagglutinins titer is a functional test for B-cell activity, measuring naturally occurring antibodies (anti-A/anti-B), making it an effective initial screen for B-cell defects.