The ability of Clostridium tetani to produce exotoxins is encoded by?

Correct Answer: C

Rationale: The correct answer is C: genes with plasmid location. Clostridium tetani produces exotoxins through genes located on plasmids. Plasmids are extrachromosomal genetic elements that carry additional genes. These genes encode for the production of exotoxins in Clostridium tetani. Choices A, B, and D are incorrect because Clostridium tetani does produce exotoxins, it does not have only endotoxin activity, and the genes responsible for exotoxin production are located on plasmids, not solely on the chromosome or both chromosome and plasmid.

Correct Answer: D

Rationale: The correct answer is D because all three viruses, Vaccinia virus, Smallpox virus, and Cowpox virus, belong to the genus Orthopoxvirus. They share similar characteristics and genetic makeup. Vaccinia virus is used as a vaccine against smallpox, Smallpox virus causes smallpox disease, and Cowpox virus can infect both animals and humans. Choice A, B, and C are incorrect because each of these viruses is a member of the Orthopoxvirus genus.

Correct Answer: A

Rationale: Rationale: 1. Gram-positive cocci in pairs indicate Streptococcus pneumoniae. 2. Presence of a capsule points to S. pneumoniae as it has a polysaccharide capsule. 3. S. pneumoniae commonly causes sore throat. 4. Neisseria meningitidis, Haemophilus influenzae, and Klebsiella pneumoniae are not typically associated with sore throat.

Correct Answer: A

Rationale: Rationale: A: Incorrect - The complement system is not directly involved in the viral neutralization reaction. B: Correct - Specific antibodies neutralize viruses by blocking their ability to infect cells. C: Incorrect - Antibodies are titrated, but only one serum sample is required for neutralization testing. D: Incorrect - Viral neutralization is primarily used to measure antibody response, not to identify newly isolated viruses.

Correct Answer: C

Rationale: The correct answer is C: Helicobacter pylori. Group I organisms are classified based on their low infectious doses and potential for bioterrorism. H. pylori is known to cause gastric ulcers and is categorized as a Group I organism due to its ability to cause disease at low doses. A: Francisella tularensis is a Group A bioterrorism agent, not Group I. B: Clostridium difficile is not typically classified as a Group I organism. D: Bacillus anthracis is a Group A bioterrorism agent, not Group I.

Correct Answer: A

Rationale: The correct answer is A: Antitoxic passive immunity. Antibotulinic serum contains pre-formed antibodies against the botulinum toxin, providing immediate protection to the patient. This is passive immunity as the patient does not produce their antibodies but receives them externally. Choice B is incorrect as botulism is not an infection, so the patient does not develop infection immunity. Choice C is incorrect because active immunity involves the body producing its antibodies after exposure to an antigen, which is not the case here. Choice D is incorrect as antimicrobic immunity relates to protection against microbes, not toxins like in botulism.

Correct Answer: B

Rationale: The correct answer is B: EBV. Osteomyelitis is primarily caused by bacteria, not viruses like Epstein-Barr virus (EBV). The main pathogens involved in osteomyelitis are typically Staphylococcus aureus, including Methicillin-resistant Staphylococcus aureus (MRSA), Haemophilus influenzae, and Pseudomonas aeruginosa. EBV is not a causative agent of osteomyelitis. It is crucial to differentiate between bacterial and viral etiologies in infectious diseases to guide appropriate treatment.

Correct Answer: D

Rationale: The correct answer is D: All of the above. Streptococcus pneumoniae, Mycobacterium tuberculosis, and Escherichia coli can all cause pneumonia, but through different mechanisms. S. pneumoniae is a common cause of community-acquired pneumonia, M. tuberculosis can lead to tuberculosis-related pneumonia, and E. coli can cause pneumonia in immunocompromised individuals. Therefore, all three bacteria can be responsible for causing pneumonia, making option D the correct choice. Option A, Streptococcus pneumoniae, is correct but does not cover all possible causes of pneumonia. Option B, Mycobacterium tuberculosis, is too specific and does not include other common causes. Option C, Escherichia coli, is also a possible cause of pneumonia but does not account for all potential pathogens.

Correct Answer: D

Rationale: Interferon is a cell-specific protein that is produced and released from infected cells in response to viral infections. It acts extracellularly to interfere with viral replication, not to inactivate the virus itself. Interferon is not coded for by cellular DNA, but by viral RNA during infection. Therefore, the correct answer, D, is that interferon is not virus-specific but is cell-specific. This is because interferon can be produced by various cell types in response to different types of viral infections, making it a broad-spectrum antiviral defense mechanism.