ATI RN
Pediatrics Genetics Questions
Question 1 of 5
Tetraploidy:
Correct Answer: D
Rationale: Tetraploidy means four complete sets of chromosomes. Normal diploid humans have 46 chromosomes (2n=46); tetraploidy is 4n=92.
Question 2 of 5
Heart disease, diabetes, cancer, alcoholism and many mental illnesses can best be described as:
Correct Answer: C
Rationale: These conditions result from multiple genetic and environmental factors, often involving many genes (polygenic) and lifestyle influences.
Question 3 of 5
Which of the following is correct with regard to aneuploidy?
Correct Answer: B
Rationale: Aneuploidy is an abnormal chromosome number, e.g., 2n+1 (trisomy, 47 chromosomes). Inversions are structural, 4n is polyploidy, and not all aneuploids die.
Question 4 of 5
A genetic defect in humans results in the absence of sweat glands in the skin. Some men have this defect all over their bodies, but in women, it is usually expressed in a peculiar way. A woman with this defect typically has small patches of skin with sweat glands and other patches where sweat glands are lacking. This pattern suggests the phenotypic effect of:
Correct Answer: B
Rationale: This describes X-linked anhidrotic ectodermal dysplasia. Females show mosaicism due to random X-inactivation (Lyonization), creating patches.
Question 5 of 5
A cancer that spreads is termed:
Correct Answer: C
Rationale: Metastatic cancer spreads from its original site to distant tissues, unlike benign tumors.