ATI RN
Endocrinology Practice Questions Questions
Question 1 of 5
Tertiary hyperparathyroidism is commonly found in:
Correct Answer: C
Rationale: Step-by-step rationale: 1. Tertiary hyperparathyroidism occurs due to prolonged secondary hyperparathyroidism in response to chronic renal failure. 2. In chronic renal failure, impaired kidney function leads to reduced activation of vitamin D and impaired calcium regulation. 3. Persistent hypocalcemia triggers the parathyroid glands to overproduce parathyroid hormone, leading to tertiary hyperparathyroidism. 4. Rickets (choice A) is associated with vitamin D deficiency, pseudohypoparathyroidism (choice B) is a genetic disorder, and malabsorption syndrome (choice D) affects nutrient absorption, but they are not commonly linked to tertiary hyperparathyroidism.
Question 2 of 5
Erythropoietin is secreted from:
Correct Answer: C
Rationale: Erythropoietin is primarily secreted from the kidney, specifically by the Juxtaglomerular cells in the kidney's cortex. These cells are responsible for sensing oxygen levels and regulating erythropoietin production accordingly. Mesenchymal tumors, cerebellar haemangioblastoma, and lymphoma are not associated with erythropoietin secretion, making them incorrect choices. Mesenchymal tumors originate from connective tissues, cerebellar haemangioblastoma is a type of brain tumor, and lymphoma is a cancer of the lymphatic system. Only the Juxtaglomerular cells in the kidney have the physiological role of secreting erythropoietin in response to hypoxia.
Question 3 of 5
All of the following are consistent with non-proliferative diabetic retinopathy except:
Correct Answer: C
Rationale: The correct answer is C: Neovascularization. Non-proliferative diabetic retinopathy is characterized by early changes such as retinal vascular microaneurysms, blot hemorrhages, and cotton-wool spots. Neovascularization is a feature of proliferative diabetic retinopathy, not non-proliferative. Neovascularization refers to the growth of abnormal new blood vessels in the retina, which can lead to severe vision loss if not treated promptly. In summary, neovascularization is not consistent with non-proliferative diabetic retinopathy, as it is a hallmark of the proliferative stage.
Question 4 of 5
Anorexia nervosa is not associated with:
Correct Answer: C
Rationale: Step-by-step rationale: 1. Anorexia nervosa can affect both males and females. 2. Therefore, it is not exclusively in females. 3. Hypokalaemia, primary amenorrhea, and low FSH and LH are commonly associated with anorexia nervosa. 4. Choice C is incorrect as anorexia nervosa can affect individuals of any gender.
Question 5 of 5
Elevated glucose levels, especially in obese persons, may be due to :
Correct Answer: C
Rationale: Elevated glucose levels in obese individuals are often due to insulin resistance. Insulin resistance occurs when the body's cells do not respond effectively to insulin, leading to decreased glucose uptake. This results in elevated blood glucose levels. Diabetic acidosis (choice A) is a complication of uncontrolled diabetes characterized by high blood ketone levels, not directly related to obesity. Glucose intolerance (choice B) refers to the body's inability to regulate blood glucose levels efficiently but is not specific to obesity. Insulin deficiency (choice D) is characteristic of type 1 diabetes, where the body does not produce enough insulin, which is distinct from insulin resistance seen in obesity.