ATI RN
Pediatric Immune Disorder Test Questions Questions
Question 1 of 5
Systemic lupus erythematosus
Correct Answer: C
Rationale: Systemic lupus erythematosus is associated with HLA-DR3.
Question 2 of 5
Bacteria such as Mycobacterium tuberculosis have acquired the capacity to inhibit phagosome-lysosome fusion. What is a consequence of this?
Correct Answer: A
Rationale: Inhibiting phagosome-lysosome fusion reduces peptide generation for MHC Class II presentation, lowering surface expression.
Question 3 of 5
Protein tyrosine kinases (PTKs) play an important role in lymphocyte function and activation. A mutation in the genes encoding the enzyme ZAP-70 would lead to which of the following?
Correct Answer: C
Rationale: ZAP-70 mutations impair T cell signaling, leading to SCID due to defective T cell development.
Question 4 of 5
Critical in antigen-capture and uptake in peripheral tissues
Correct Answer: D
Rationale: Dendritic cells capture and present antigens in tissues.
Question 5 of 5
The spleen has a red pulp (macrophages and red blood cells) and a white pulp (dense lymphoid tissue). T cells are found chiefly in the and B cells are found in the both within the pulp.
Correct Answer: A
Rationale: T cells are in PALS, B cells in follicles, both in white pulp.