Symptoms of acute morphine toxicity include:

Correct Answer: A

Rationale: Acute morphine toxicity, an overdose scenario, presents a classic triad: coma, pinpoint pupils (miosis), and depressed respiration (choice A). Coma results from profound CNS depression, miosis from parasympathetic overstimulation, and respiratory depression from medullary suppression, often fatal without intervention (e.g., naloxone). Abdominal cramps and diarrhea (choice B) suggest withdrawal, not toxicity. Hypertension and arrhythmias (choice C) align with stimulants, not opioids. Dry mouth and mydriasis (choice D) are anticholinergic signs, opposite to morphine's effects. This triad is critical for rapid diagnosis and treatment in emergency settings, distinguishing opioid toxicity from other syndromes.

Correct Answer: A

Rationale: Colchicine (choice B) treats acute gout by reducing inflammation, Allopurinol (choice C) lowers uric acid long-term, and Sulphinpyrazone (choice D) promotes urate excretion. Thiazide diuretics (choice A) increase uric acid retention, worsening gout, making them the exception. This distinguishes gout management from contraindicated drugs.

Correct Answer: D

Rationale: Flurazepam (choice A), Triazolam (choice B), and Chlordiazepoxide (choice C), all benzodiazepines, initiate sleep via GABAa potentiation, differing in duration (long, short, intermediate). ‘All of the above' (choice D) is correct, as each is a hypnotic, tailored to insomnia needs, highlighting benzodiazepine versatility.

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.