ATI RN
ATI RN Pharmacology Online Practice 2019 A Questions
Question 1 of 5
Superficial bladder cancer can be treated by direct instillation of the antineoplastic antibiotic agent mitomycin (Mutamycin). This process is termed:
Correct Answer: B
Rationale: Intravesical administration involves the direct instillation of medication into the bladder, which is a common method for treating superficial bladder cancer. This approach allows high concentrations of the drug, such as mitomycin, to come into direct contact with the cancerous cells lining the bladder, minimizing systemic side effects. Intraventricular and intrathecal administrations are used for delivering drugs to the brain and spinal cord, respectively, while intravascular administration refers to intravenous delivery. Intravesical administration is specifically designed for bladder conditions, making it the correct answer.
Question 2 of 5
A nurse is providing discharge instructions to a patient who is taking atenolol (Tenormin) to treat hypertension. What would the nurse teach the patient regarding a possible drug-drug interaction?
Correct Answer: C
Rationale: A decreased hypertensive effect can occur if a beta-selective adrenergic blocking agent is used in combination with NSAIDs. If this combination is used, the patient should be monitored closely and dosage adjustments made. Antibiotics, oral contraceptives, and antifungal agents are not known to have a drug-drug interaction. The nurse should educate the patient about potential interactions and advise them to consult their healthcare provider before starting any new medications.
Question 3 of 5
Currently, there is no way to prevent myelosuppression. However, there are medications available to elicit a more rapid bone marrow recovery. An example is:
Correct Answer: A
Rationale: Epoetin alfa (Epogen, Procrit) is an example of a medication used to elicit a more rapid bone marrow recovery. It is a form of erythropoietin, which stimulates the production of red blood cells in the bone marrow. By stimulating red blood cell production, epoetin alfa can help in faster recovery from myelosuppression, a condition characterized by low blood cell counts. This medication is commonly used in patients undergoing chemotherapy or those with chronic kidney disease to manage anemia and improve overall quality of life. Therefore, epoetin alfa is the correct answer in this scenario as it specifically addresses the issue of bone marrow recovery.
Question 4 of 5
A 66-year-old man with a history of recurrent pulmonary infections and hypertension is managed with ethacrynic acid, which controls his hypertension well. He is often hospitalized and placed on gentamicin for his recurrent pulmonary infections. Which of the following adverse effects must the treating physician be keenly aware of?
Correct Answer: B
Rationale: Gentamicin, an aminoglycoside, risks ototoxicity-hearing loss , especially with repeated use. Ethacrynic acid, a loop diuretic, also has ototoxicity potential, compounding risk. Dizziness , nausea , vertigo , and vomiting (E) occur but are less specific. Monitoring hearing is critical in this scenario.
Question 5 of 5
Superficial bladder cancer can be treated by direct instillation of the antineoplastic antibiotic agent mitomycin (Mutamycin). This process is termed:
Correct Answer: B
Rationale: Intravesical administration involves the direct instillation of medication into the bladder, which is a common method for treating superficial bladder cancer. This approach allows high concentrations of the drug, such as mitomycin, to come into direct contact with the cancerous cells lining the bladder, minimizing systemic side effects. Intraventricular and intrathecal administrations are used for delivering drugs to the brain and spinal cord, respectively, while intravascular administration refers to intravenous delivery. Intravesical administration is specifically designed for bladder conditions, making it the correct answer.