ATI RN
Endocrine Pharmacology Quizlet Questions
Question 1 of 5
Sulphonylureas:
Correct Answer: B
Rationale: Sulphonylureas relieve polyuria/polydipsia by lowering glucose and require beta cells to stimulate insulin release. They're not for ketosis-prone patients, vascular benefits are unproven, and dosing varies.
Question 2 of 5
Effects of iodide salts given in large doses do not include
Correct Answer: D
Rationale: Large doses of iodide inhibit thyroid hormone synthesis and release (Wolff-Chaikoff effect), reducing size, vascularity, and iodination, but not increasing 131I uptake.
Question 3 of 5
Hypercoagulability and dermal vascular necrosis due to protein C deficiency is known to be an early-appearing adverse effect of treatment with
Correct Answer: D
Rationale: Warfarin can cause skin necrosis early in treatment due to transient protein C deficiency.
Question 4 of 5
Which of the following classes of compounds stimulates the release of insulin from pancreatic beta-cells?
Correct Answer: D
Rationale: Sulfonylureas enhance insulin secretion from beta-cells.
Question 5 of 5
A 67-year-old man injures his shoulder in an ATV accident. Over-the-counter ibuprofen is unable to control the pain satisfactorily. The patient asks about glucocorticoid injections, so his doctor begins to explain the myriad effects of glucocorticoids in the body. Which of the following glucocorticoid actions would be most desirable in this patient?
Correct Answer: D
Rationale: Glucocorticoids reduce inflammation by increasing 1kB synthesis, which inhibits NF-kB, a key pro-inflammatory transcription factor. This is most desirable for controlling pain and inflammation in a shoulder injury.