ATI RN
Diabetes drugs Questions
Question 1 of 5
Sulfonylureas are more commonly used than biguanides as oral hypoglycaemics because
Correct Answer: A
Rationale: Sulfonylureas are preferred due to greater efficacy in stimulating insulin release; biguanides don’t cause ketoacidosis.
Question 2 of 5
Glucagon release from pancreas is stimulated by
Correct Answer: D
Rationale: Adrenaline stimulates glucagon release to raise glucose during stress, unlike insulin or somatostatin (inhibitory).
Question 3 of 5
The antidiabetic agent most likely to cause lactic acidosis is
Correct Answer: B
Rationale: Phenformin has a higher risk of lactic acidosis than metformin, leading to its withdrawal in many regions.
Question 4 of 5
The sulfonylurea with a relatively longer duration of action is
Correct Answer: A
Rationale: Chlorpropamide has a longer half-life (up to 36 hours) compared to other sulfonylureas.
Question 5 of 5
The agent with negligible mineralocorticoid effect is
Correct Answer: B
Rationale: Betamethasone has minimal mineralocorticoid activity, unlike fludrocortisone (strong) or cortisol.