Sulfonylureas are more commonly used than biguanides as oral hypoglycaemics because

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Diabetes drugs Questions

Question 1 of 5

Sulfonylureas are more commonly used than biguanides as oral hypoglycaemics because

Correct Answer: A

Rationale: Sulfonylureas are preferred due to greater efficacy in stimulating insulin release; biguanides don’t cause ketoacidosis.

Question 2 of 5

Glucagon release from pancreas is stimulated by

Correct Answer: D

Rationale: Adrenaline stimulates glucagon release to raise glucose during stress, unlike insulin or somatostatin (inhibitory).

Question 3 of 5

The antidiabetic agent most likely to cause lactic acidosis is

Correct Answer: B

Rationale: Phenformin has a higher risk of lactic acidosis than metformin, leading to its withdrawal in many regions.

Question 4 of 5

The sulfonylurea with a relatively longer duration of action is

Correct Answer: A

Rationale: Chlorpropamide has a longer half-life (up to 36 hours) compared to other sulfonylureas.

Question 5 of 5

The agent with negligible mineralocorticoid effect is

Correct Answer: B

Rationale: Betamethasone has minimal mineralocorticoid activity, unlike fludrocortisone (strong) or cortisol.

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