Sulfonylureas are a primary mode of therapy in the treatment of

Questions 16

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Drugs for diabetes Questions

Question 1 of 5

Sulfonylureas are a primary mode of therapy in the treatment of

Correct Answer: D

Rationale: Sulfonylureas are used in type 2 DM to stimulate insulin release, not in type 1, pregnancy, severe organ dysfunction, or ketoacidosis.

Question 2 of 5

The duration of action of insulin-zinc suspension (lente insulin) is

Correct Answer: C

Rationale: Lente insulin (insulin-zinc suspension) has an intermediate duration of 20-24 hours.

Question 3 of 5

There is no alternative to insulin therapy for

Correct Answer: A

Rationale: Type 1 (IDDM) patients require insulin due to absolute deficiency; type 2 (NIDDM) can often use alternatives.

Question 4 of 5

Insulin resistance can be overcome by the use of

Correct Answer: D

Rationale: Monocomponent (purified) insulins reduce antibody-mediated resistance compared to older forms.

Question 5 of 5

The second generation sulfonylurea hypoglycaemics differ from the first generation one in that they

Correct Answer: A

Rationale: Second-generation sulfonylureas (e.g., glyburide) are more potent than first-generation (e.g., tolbutamide).

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