Sulfonamides have the following unwanted effects:

Correct Answer: D

Rationale: The correct answer is D: All of the above. Sulfonamides can cause hematopoietic disturbances like anemia, thrombocytopenia, and leukopenia. Crystalluria can occur due to the precipitation of sulfonamide crystals in urine. Nausea, vomiting, and diarrhea are common gastrointestinal side effects of sulfonamides. Therefore, all of these unwanted effects can be attributed to sulfonamide use. The other choices are incorrect because each of them individually represents a specific side effect of sulfonamides, while the correct answer encompasses all the possible unwanted effects associated with sulfonamides.

Correct Answer: B

Rationale: The correct answer is B: Asparaginase. Asparaginase is used in acute leukemia treatment to deplete asparagine, an essential amino acid for cancer cell growth. This enzyme helps inhibit protein synthesis in leukemia cells, leading to cell death. Dihydrofolate reductase (A) is targeted by methotrexate, not commonly used in leukemia. Aromatase (C) inhibitors are used in breast cancer, not leukemia. DNA gyrase (D) is a bacterial enzyme targeted by antibiotics, not used in leukemia treatment. In conclusion, B is the correct choice for acute leukemia treatment.

Correct Answer: C

Rationale: Step-by-step rationale for why choice C (Adenosine) is correct: 1. Adenosine is used for supraventricular tachycardia due to its ability to slow conduction through the AV node. 2. Mexiletine and Lidocaine are sodium channel blockers used for ventricular arrhythmias, not supraventricular tachycardia. 3. Amiodarone is a broad-spectrum antiarrhythmic used for various types of arrhythmias, not specific to supraventricular tachycardia. Summary: Adenosine is the correct answer because of its specific mechanism of action in treating supraventricular tachycardia. Mexiletine, Lidocaine, and Amiodarone are used for different types of arrhythmias, making them incorrect choices.

Correct Answer: C

Rationale: The correct answer is C: Adenosine. Adenosine is commonly used for cardioversion of supraventricular tachycardias like atrial flutter. It works by blocking the AV node transiently, allowing the sinus node to regain control of the heart rhythm. Mexiletine (A) and Lidocaine (B) are primarily used for ventricular arrhythmias, not atrial flutter. Amiodarone (D) is often used for atrial fibrillation, not specifically atrial flutter.

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.