Suggestive laboratory features of classic growth hormone deficiency include all of the following EXCEPT

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Pediatric Endocrine Nursing Questions Questions

Question 1 of 5

Suggestive laboratory features of classic growth hormone deficiency include all of the following EXCEPT

Correct Answer: D

Rationale: Low calcium is not a feature of GH deficiency; others reflect impaired GH-IGF axis.

Question 2 of 5

A 14-year-old presents with poor growth and delayed puberty. She denies headaches or poor school performance. She is physically sluggish and has a small goiter, and her serum cholesterol is 500 mg/dL. The most likely diagnosis is

Correct Answer: A

Rationale: Hashimoto’s thyroiditis causes hypothyroidism with goiter, delayed puberty, and elevated cholesterol.

Question 3 of 5

The underlying disorder affecting the child in the previous question is most likely

Correct Answer: A

Rationale: Type I autoimmune polyendocrinopathy (APS-1) includes Addison’s, hypoparathyroidism (hypocalcemia), and candidiasis (nail rash).

Question 4 of 5

The hypothalamus secretes releasing or inhibiting factors to control the anterior pituitary gland. Of the following, the pituitary hormone that is elevated in a hypothalamic disease is

Correct Answer: D

Rationale: Hypothalamic disease often disrupts inhibitory control, such as dopamine’s inhibition of prolactin. Thus, prolactin levels rise due to lack of suppression, unlike other hormones (A, B, C, E) which are stimulated by hypothalamic releasing factors and may decrease in hypothalamic dysfunction.

Question 5 of 5

A 9-year-old girl develops polyuria, vomiting, abdominal pain, and deep acidotic breathing during an intercurrent illness. She has been diagnosed with type 1 diabetes mellitus 5 years ago. Lab investigations reveal: blood glucose, 600 mg/dL; blood pH, 7.28; serum bicarbonate concentration, 14 mEq/L; and ketones in urine are positive. Of the following, the MOST serious complication that may occur in this girl is

Correct Answer: B

Rationale: Cerebral edema is the most serious complication of DKA in children, potentially fatal due to brain swelling from rapid fluid shifts during treatment. Arrhythmias (A), renal injury (C), pulmonary edema (D), and bowel ischemia (E) are less common or less immediately life-threatening.

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