Correct Answer: B

Rationale: Both statements are false. Studies suggest that leukoplakia, a white plaque that forms on oral mucous membranes, can be resolved by vitamin A, retinoids, and beta-carotene. Despite the potential to resolve leukoplakia, relapse is common. Also pertinent, evidence does not indicate that any of these nutrients prevent malignant transformation. The extract provided clarifies that leukoplakia is a white plaque, not an erythematous lesion, and that vitamin A, retinoids, and beta-carotene can help resolve it.

Correct Answer: A

Rationale: Both statements are true. The effect of vitamin A on the growth of soft tissues and bones naturally extends to the teeth and surrounding structures. Enamel hypoplasia, involving defective enamel matrix and incomplete calcification of enamel and dentin, can be due to vitamin A deficiency. The effect of this vitamin upon surrounding bone directly affects spacing patterns of the teeth within the bone and dentition. Choice A is correct because both statements accurately describe the influence of vitamin A on tooth development. Choices B, C, and D are incorrect as they do not reflect the accuracy of the statements provided.

Correct Answer: A

Rationale: Wernicke-Korsakoff syndrome is indeed associated with thiamine (vitamin B1) deficiency. This syndrome is commonly seen in individuals with chronic alcoholism due to poor diet and impaired thiamine absorption. Thiamine is essential for normal brain function and energy metabolism. Riboflavin (B2) deficiency can lead to symptoms like sore throat and swollen mucous membranes, not Wernicke-Korsakoff syndrome. Niacin (B3) deficiency causes pellagra, characterized by dermatitis, diarrhea, dementia, and death, but not Wernicke-Korsakoff syndrome. Pyridoxine (B6) deficiency can result in dermatitis, glossitis, and peripheral neuropathy, but it is not associated with Wernicke-Korsakoff syndrome.

Correct Answer: A

Rationale: Both the statement and the reason are correct and related. The Institute of Medicine (IOM) recommends 18 mg of iron per day for women 19 to 50 years old, 8 mg/day for women 51 years old and older, and men 19 years old and older. During menstruation, women lose blood containing iron, leading to a higher iron requirement in premenopausal women compared to men or postmenopausal women. This increased demand aims to replenish the iron lost during this physiological process. Therefore, the statement and reason are directly linked, explaining why the RDA for iron is higher in premenopausal women than in men or postmenopausal women. Choices B, C, and D are incorrect as they do not accurately assess the relationship between the statement and the reason provided in the question.

Correct Answer: B

Rationale: The correct answer is B: Iron. The provided extract mentions that iodine deficiency can cause delayed tooth eruption, enlarged tongue, stillbirths, altered craniofacial growth, sensitivity to cold, dry skin, depression, and goiter. Zinc, Sodium, and Potassium are not associated with these specific symptoms. Zinc deficiency can lead to other health issues but not the ones mentioned. Sodium and Potassium imbalances do not typically result in the symptoms described in the question.