Staphylococcal scalded skin syndrome is most common in:

Correct Answer: A

Rationale: The correct answer is A: infants. Staphylococcal scalded skin syndrome is most common in infants because their immune systems are not fully developed, making them more susceptible to Staphylococcus aureus infections. This bacteria produces exotoxins that cause the skin to blister and peel, characteristic of the syndrome. Adolescents, young adults, and the elderly have more mature immune systems, making them less vulnerable to this specific infection. Therefore, infants are at a higher risk for developing Staphylococcal scalded skin syndrome compared to other age groups.

Correct Answer: A

Rationale: The most probable diagnosis is Tetanus (Choice A) based on the symptoms described. Tetanus is characterized by muscle stiffness, difficulty opening the mouth (trismus), muscle spasms, and convulsions. The progression of symptoms from muscle tension to generalized convulsions every 10-15 min is classic for tetanus. Tetania (Choice B) is similar but typically presents with more subtle muscle contractions rather than convulsions. Meningoencephalitis (Choice C) presents with fever, headache, and altered mental status, not the muscle symptoms described. Hemorrhagic stroke (Choice D) presents with sudden onset neurological deficits like weakness or sensory changes, not the muscle symptoms described.

Correct Answer: B

Rationale: The correct answer is B: Bacillus subtilis. Bacillus subtilis is known for its ability to resist heat and radiation due to its formation of endospores, which are highly resistant structures that protect the bacterium from harsh environmental conditions. This resilience allows Bacillus subtilis to survive in extreme environments where other bacteria cannot. Explanation of other choices: A: Escherichia coli is not known for its exceptional resistance to heat and radiation. C: Pseudomonas aeruginosa is not particularly resistant to heat and radiation compared to Bacillus subtilis. D: Clostridium perfringens is not as well-known for its heat and radiation resistance as Bacillus subtilis.

Correct Answer: C

Rationale: The correct answer is C: To perform serodiagnostics of tuberculosis. Rationale: The negative reaction to the Mantoux test indicates absence of TB infection. Performing serodiagnostics will further confirm the absence of active infection. This is important to rule out TB before considering vaccination or isolation measures. Summary: A: BCG vaccination is not necessary as the boy shows a negative reaction to the Mantoux test. B: Repeating the test in a month is unnecessary as the initial test already showed a negative reaction. D: Isolating the boy is not warranted as there is no evidence of active TB infection.

Correct Answer: A

Rationale: The correct sequence of stages in the multiplication of animal viruses is as follows: 1. Adsorption: Virus attaches to host cell. 2. Penetration: Virus enters host cell. 3. Uncoating: Viral genetic material is released. 4. Replication: Viral genetic material replicates. 5. Assembly: New viral particles are assembled. 6. Release: New viral particles are released from the host cell. Choice A is correct as it follows the correct chronological order of virus multiplication stages. Choice B is incorrect as it has the wrong order of penetration and adsorption. Choice C is incorrect as it has the wrong order of adsorption, uncoating, and penetration. Choice D is incorrect as it has the wrong order of penetration and uncoating.

Correct Answer: B

Rationale: The correct answer is B because transformation in bacteria refers to the uptake of naked DNA from the environment. During transformation, bacteria take up free DNA from their surroundings and incorporate it into their own genome. This mechanism allows bacteria to acquire new genetic material and traits. Explanation for other choices: A: Transfer of DNA via phages refers to transduction, not transformation. C: Transfer of DNA via direct contact is known as conjugation, not transformation. D: Spore formation is a method of bacterial survival but is not related to transformation.

Correct Answer: C

Rationale: The correct answer is C: Escherichia coli. E.coli is the most common urinary tract pathogen due to its ability to adhere to and infect the urinary tract epithelium. It accounts for approximately 80-85% of urinary tract infections. It possesses specific virulence factors that enable it to colonize and cause infection in the urinary tract. Proteus mirabilis (A) is known for causing complicated UTIs, but it is less common than E.coli. Staphylococcus aureus (B) is not a common urinary pathogen. Pseudomonas aeruginosa (D) is more commonly associated with hospital-acquired infections, rather than community-acquired urinary tract infections.

Correct Answer: B

Rationale: Step 1: The description of microorganisms resembling tennis racket indicates Corynebacterium diphtheriae, the causative agent of diphtheria. Step 2: Diphtheria is a bacterial infection that can cause severe respiratory and systemic symptoms. Step 3: Botulism is caused by Clostridium botulinum, not tennis racket-shaped microorganisms. Step 4: Typhoid fever is caused by Salmonella typhi, which does not resemble tennis rackets. Step 5: Salmonellosis is caused by various Salmonella species, which also do not have the described tennis racket appearance.

Correct Answer: B

Rationale: The correct answer is B: Conjugation. Conjugation involves the transfer of genetic material from a donor cell to a recipient cell through direct cell-to-cell contact, typically mediated by a conjugative plasmid. During conjugation, a conjugative pilus forms a bridge between the donor and recipient cells, allowing the transfer of genetic material. A: Replication is the process of copying DNA to produce two identical DNA molecules. It does not involve the transfer of genetic material between cells. C: Transformation is the uptake and incorporation of foreign DNA from the environment by a bacterial cell. It does not require direct cell-to-cell contact. D: Transduction is the transfer of genetic material from one bacterium to another by a bacteriophage vector. It does not involve direct cell-to-cell contact between the donor and recipient cells.