Spontaneous intracranial hemorrhage is more likely to occur in

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Hematology Final Exam Questions Pdf Questions

Question 1 of 5

Spontaneous intracranial hemorrhage is more likely to occur in

Correct Answer: D

Rationale: Factor XIII deficiency (E) causes severe bleeding, including intracranial hemorrhage, due to unstable clots, more than factor VII (A), VIII (B), IX (C), or XI (D) deficiencies.

Question 2 of 5

Lupus anticoagulants usually affect the following laboratory test

Correct Answer: B

Rationale: Lupus anticoagulants prolong PTT (B) by interfering with phospholipid-dependent clotting, not BT (A), PT (C), TT (D), or clot solubility (E).

Question 3 of 5

You are evaluating a 5-year-old male child with multiple ecchymoses distributed all over the extremities and trunk; examination reveal a palpable spleen $3 \mathrm{~cm}$ below the left costal margin. Lab findings include: hemoglobin, 11.3 g/dL; white blood cell count, 8700/mm3; platelets count, 21000/mm3. Of the following, the most proper NEXT step is

Correct Answer: D

Rationale: Thrombocytopenia (21,000/mm3) with splenomegaly suggests hypersplenism or marrow disorder. Bone marrow study (E) distinguishes production vs. sequestration, more definitive than BT (A), coagulation (B), aggregation (C), or US (D) initially.

Question 4 of 5

Microthrombocytes are MOST likely to be seen in

Correct Answer: C

Rationale: WAS (C) features small (micro) platelets due to cytoskeletal defects, unlike ITP (A, large), Bernard-Soulier (B, giant), Glanzmann’s (D), or type 2B vWD (E).

Question 5 of 5

You are evaluating a 7-year-old male child with cervical lymphadenopathy; the MOST likely finding that raise your suspicion of malignancy is

Correct Answer: C

Rationale: Fixed nodes (C) suggest malignancy (e.g., lymphoma) by indicating infiltration, more than matted (A), fluctuant (B), symptoms (D), or duration (E), which are less specific.

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