Spondyloarthritides are largely genetically determined. Which of the following characteristics is never associated with such diseases?

Correct Answer: D

Rationale: Rheumatoid factor positivity is rare in spondyloarthritides.

Correct Answer: C

Rationale: Angioedema is not a major criterion for atopic dermatitis; it is more associated with allergic reactions.

Correct Answer: D

Rationale: Intense itching is a hallmark feature of atopic dermatitis often leading to scratching and worsening of symptoms.

Correct Answer: A

Rationale: Peribronchial thickening is commonly seen in children with asthma due to chronic airway inflammation and mucus buildup.

Correct Answer: C

Rationale: Wheezing apart from colds is a strong predictor of persistent asthma, suggesting airway hyperreactivity rather than transient viral-induced wheezing.