ATI RN
First Aid Cardiovascular Drugs Quizlet Questions
Question 1 of 5
Spironolactone (Aldactone) acts at this nephron site:
Correct Answer: D
Rationale: The correct answer is D: Collecting duct. Spironolactone is a potassium-sparing diuretic that acts on the aldosterone receptor in the collecting duct of the nephron. This inhibits sodium reabsorption and potassium secretion, leading to increased excretion of sodium and water while retaining potassium. The other choices (A, B, C) are incorrect because spironolactone does not primarily act on the proximal convoluted tubule, ascending thick limb of the loop of Henle, or distal convoluted tubule.
Question 2 of 5
Tick the drug used for toxoplasmosis treatment:
Correct Answer: D
Rationale: Step-by-step rationale for choosing Pyrimethamine (D) for toxoplasmosis treatment: 1. Pyrimethamine inhibits dihydrofolate reductase enzyme in Toxoplasma gondii. 2. This disrupts folate metabolism and impairs parasite growth. 3. Pyrimethamine is a standard treatment for toxoplasmosis. 4. Chloroquine (A) is used for malaria, Tetracycline (B) for bacterial infections, and Suramin (C) for African trypanosomiasis.
Question 3 of 5
Tick the drug that can induce nausea, diarrhea, abdominal pain and rhinitis:
Correct Answer: D
Rationale: Step-by-step rationale: 1. Saquinavir is a protease inhibitor used to treat HIV/AIDS. 2. Protease inhibitors can cause gastrointestinal side effects like nausea, diarrhea, abdominal pain. 3. Saquinavir is known to induce rhinitis as a common side effect. 4. Options A, B, and C are antiviral drugs but do not typically cause these specific side effects. Summary: Saquinavir is the correct answer as it is a protease inhibitor known to induce gastrointestinal symptoms and rhinitis. The other options are antiviral drugs that do not have these specific side effects.
Question 4 of 5
Which of the following would be a useful drug to add to the patient's therapeutic regimen?
Correct Answer: A
Rationale: The correct answer is A: Metoprolol. Metoprolol is a beta-blocker commonly used in heart failure to reduce morbidity and mortality. It improves symptoms, decreases hospitalizations, and increases survival rates in heart failure patients. It works by blocking the effects of adrenaline on the heart, leading to decreased heart rate and blood pressure, which reduces the workload on the heart. Choice B, Digoxin, is not typically used as a first-line treatment in heart failure. Choice C, Dobutamine, is a short-acting inotrope used in acute heart failure exacerbations, not for long-term therapy. Choice D, Milrinone, is a phosphodiesterase inhibitor used in acute heart failure, but it has more side effects and is not recommended for long-term use.
Question 5 of 5
Which of the following diuretics would be contraindicated for a patient with ascites and liver cirrhosis?
Correct Answer: D
Rationale: The correct answer is D, Triamterene. Triamterene is a potassium-sparing diuretic, which can lead to hyperkalemia. Patients with liver cirrhosis often have impaired liver function, leading to decreased potassium excretion. Hyperkalemia can worsen in these patients and can be dangerous. Mannitol (A) is an osmotic diuretic, Hydrochlorothiazide (B) is a thiazide diuretic, and Ethacrynic acid (C) is a loop diuretic, all of which can be used in patients with liver cirrhosis and ascites, but Triamterene should be avoided due to the risk of hyperkalemia.