ATI RN
Drug toxicology Questions
Question 1 of 5
Specific causes of death which are positively related to smoking include:
Correct Answer: D
Rationale: Smoking is a known risk factor for ischaemic heart disease (A), oesophageal cancer (B), emphysema (C), aortic aneurysm (D), and tongue cancer (E), all well-documented in toxicology.
Question 2 of 5
Delirium tremens:
Correct Answer: B
Rationale: Delirium tremens has a 5-10% mortality rate (B) and requires parenteral thiamine (D) to prevent Wernicke’s encephalopathy. A is incorrect (only ~5% of withdrawals), C is wrong (benzodiazepines are the treatment), and E is unnecessary (phenytoin isn’t standard prophylaxis).
Question 3 of 5
3,4-Methylenedioxy-N-methylamphetamine (MDMA or ecstasy):(Select one that does not apply)
Correct Answer: D
Rationale: MDMA acts on 5HT2 receptors (A), has hallucinogenic/stimulant effects (B), causes hyperpyrexia (C), affects impulsivity/memory (D), and may damage serotonergic nerves (E), all consistent with its toxicology profile.
Question 4 of 5
The following suspected overdoses are indications for emergency measurement of drug concentration:(Select one that does not apply)
Correct Answer: C
Rationale: Iron (A), methanol (B), and salicylates (E) require emergency concentration measurement due to specific treatments (e.g., deferoxamine, ethanol, alkalinization). Amitriptyline (C) and temazepam (D) are managed symptomatically.
Question 5 of 5
An 18-year-old woman is admitted 4 hours after taking 50 paracetamol and 50 x 300 mg aspirin tablets. The following statements are correct:
Correct Answer: C
Rationale: Acetylcysteine (C) is indicated for paracetamol overdose within 8 hours, and mixed metabolic acidosis/respiratory alkalosis (D) is typical of aspirin overdose. A is unlikely (coma not immediate), B is outdated (washout rarely used after 4 hours), and E requires lab confirmation of coagulopathy first.