Sotos syndrome is characterized by all of the following EXCEPT

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Pediatric Endocrine System Questions

Question 1 of 5

Sotos syndrome is characterized by all of the following EXCEPT

Correct Answer: D

Rationale: Sotos syndrome often includes intellectual disability, not normal intelligence.

Question 2 of 5

The initial treatment of choice for Graves disease is

Correct Answer: D

Rationale: Propylthiouracil (PTU) is a first-line antithyroid drug for Graves disease in children, controlling hyperthyroidism.

Question 3 of 5

Type I diabetes mellitus is most often associated with

Correct Answer: C

Rationale: Type 1 diabetes is linked to autoantibodies, often against glutamic acid decarboxylase (GAD), not dehydrogenase.

Question 4 of 5

In insulin-dependent diabetes mellitus, hyperglycemia results when insulin secretion becomes inadequate to enhance peripheral glucose uptake and to suppress hepatic and renal glucose production. Of the following, the sign of more complete insulin deficiency is

Correct Answer: C

Rationale: Ketogenesis indicates severe insulin deficiency, as it reflects uncontrolled lipolysis and ketone production, more advanced than hyperglycemia (A, B) or glycosuria (D). Metabolic acidosis (E) follows ketogenesis but is a consequence, not the primary sign.

Question 5 of 5

A 5-year-old girl has been developed type 1 diabetes mellitus 6 months ago. She is on intensive control using multiple daily injections of insulin. A recent blood testing of HgbA1c is 6.5%. Of the following, the MOST frequent complication that may be encountered at this age is

Correct Answer: A

Rationale: Intensive insulin therapy in young children often leads to recurrent hypoglycemia due to tight control (HgbA1c 6.5%), variable eating, and activity patterns. Hyperglycemia (B), weight loss (C), candidiasis (D), and UTIs (E) are less frequent with good control.

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